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临床试验/NCT04922684
NCT04922684Unknown不适用

Can Mimic Emotional Expression Training Help Improve Emotion Processing

University of Electronic Science and Technology of China1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2020年3月30日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
90
试验地点
1
主要终点
Intensity score of subjects' mimic facial emotions

研究概览

简要总结

The main aim of the present study is to investigate whether mimicking emotional expressions training via FaceReader software can improve emotional processing and recognition in healthy subjects, especially individuals with hityer autistic traits.

详细描述

Some mood and trait questionnaires such as Autism Spectrum Quotient, Social Responsiveness Scale,State-Trait Anxiety Inventory,Beck's Depression Inventory etc are asked to complete. 90 healthy male subjects will receive 16 times (4 times a week , 4 weeks) of mimicking emotional expressions training via Facereader. During training, 3 times of fNIRS (t2,t9 and t16) were recorded simultaneously. fMRI scanning, including emotion processing and emotion recognition tasks, 7 minutes resting data, ans DTI data will be collected before and after the training. After fMRI scaning, behavioral ratings (i.e. intensity and valence) and eye-tracking data will be collected.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
17 Years 至 30 Years(Child, Adult)
性别
Male
接受健康志愿者

入选标准

  • Healthy subjects without past or current psychiatric or neurological disorders

排除标准

  • history of head injury;
  • pregnant, menstruating, taking oral contraceptives;
  • medical or psychiatric illness.

结局指标

主要结局

Intensity score of subjects' mimic facial emotions

时间窗: an average of 4 weeks

The measurement was monitored and analyzed by FaceReader software before and after the 4-week training session and subjects' facial expressions of mimicking certain emotions will be calculated into intensity, ranging from 0 to 1.

Valence score of subjects' mimic facial emotions

时间窗: an average of 4 weeks

The measurement was monitored and analyzed by FaceReader software before and after the 4-week training session and subjects' facial expressions of mimicking certain emotions will be calculated into valence, ranging from -1 to 1.

Arousal score of subjects' mimic facial emotions

时间窗: an average of 4 weeks

The measurement was monitored and analyzed by FaceReader software before and after the 4-week training session and subjects' facial expressions of mimicking certain emotions will be calculated into arousal, ranging from 0 to 1.

Task-dependent functional MRI data

时间窗: an average of 4 weeks

Neural activities of brain regions, notably mirror neuron system will be collected for analysis when the subjects participate in a face processing and emotion recognition task in a MRI scanner before and after the 4-week training session.

次要结局

未报告次要终点

研究者

发起方
University of Electronic Science and Technology of China
申办方类型
Other
责任方
Principal Investigator
主要研究者

Keith Kendrick

Professor

University of Electronic Science and Technology of China

研究点 (1)

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