Functional Outcomes and Health Related Quality of Life in Lower Extremity Soft Tissue Sarcoma Patients After Limb Salvage: A Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 141
- 试验地点
- 1
- 主要终点
- Validity of the lower-limb Musculoskeletal Tumor Society score and the Toronto Extremity Salvage Score
研究概览
简要总结
This study aims to:
- validate the Finnish version of the Musculoskeletal Tumor Society scale and the Toronto Extremity Salvage Score lower extremity sections and to
- assess the functional ability and health-related quality of life (HRQoL) of lower extremity sarcoma patients who have undergone limb salvage surgery.
详细描述
The first purpose of this study is to validate the Finnish version of the Musculoskeletal Tumor Society scale and the Toronto Extremity Salvage Score upper extremity sections. The second purpose is to chart the functional capabilities and health-related quality of life (HRQoL) of upper extremity sarcoma patients who have undergone limb salvage surgery with local or free flaps.
Patient hospital records are retrospectively reviewed to chart the demographic and clinical data.
The recruitment of patient takes place at the outpatient clinic of Department of Oncology, Helsinki University Hospital. The study includes a cross-sectional assessment at one year follow-up with five validated questionnaires. A follow-up is conducted three years after surgery in the outpatient clinic.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 10 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Lower extremity soft tissue sarcoma locating in between hip/gluteus to foot
- •No metastasis at the time of diagnosis
- •Undergone limb salvage surgery
- •A minimum of 1 year follow-up
- •Written consent
- •Age > 18
排除标准
- •No limb-salvage surgery due to sarcoma
结局指标
主要结局
Validity of the lower-limb Musculoskeletal Tumor Society score and the Toronto Extremity Salvage Score
时间窗: two to five years
The validity is studied
Reliability of the lower-limb Musculoskeletal Tumor Society score and the Toronto Extremity Salvage Score
时间窗: two to five years
The test-retest reliability is studied
Health-related quality of life after limb salvage
时间窗: two to five years
Assessment of health-related quality of life
Assessment of the functional ability after limb salvage
时间窗: two to five years
Assessment of functional ability
次要结局
- Quality of Life Questionnaire-Core 30(two to five years)
- The 15-dimensions health-related quality of life instrument(two to five years)
- The Musculoskeletal Tumor Society score lower extremity section(two to five years)
- The Toronto Extremity Salvage Score lower extremity section(two to five years)
研究者
Jussi Repo
MD
Helsinki University Central Hospital