Dual Reinforcement Contingency Management for Alcohol Use Disorders
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 74
- 试验地点
- 1
- 主要终点
- Alcohol abstinence
研究概览
简要总结
Phosphatidylethanol (PEth) is a direct biomarker of alcohol that can detect moderate to heavy drinking with high sensitivity and specificity over 3-week periods. Reinforcing negative PEth results alongside attendance may increase the proportion of participants who respond to CM during and post treatment. In the proposed study, the investigators will collect PEth samples every 3 weeks for 12 weeks in 150 participants initiating outpatient treatment for alcohol use disorders. Using a two-group randomized design, participants will be assigned to standard care with PEth monitoring alone or with CM for attending treatment and submitting PEth negative samples. Compared to standard care and monitoring, the investigators expect that the CM intervention will result in greater attendance, more PEth negative samples, and higher proportions of self-reported non-drinking days, along with lower proportions of heavy drinking days, over the short term and the long term, measured throughout a 12-month follow-up. The investigators anticipate that the reinforcement intervention may decrease other drug use and sexual risk behaviors that spread HIV, reduce psychiatric symptoms, and improve quality of life as well.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •in intensive outpatient treatment
- •DSM-5 diagnosis of an alcohol use disorder
排除标准
- •have a condition that may hinder study participation
研究组 & 干预措施
Control Group
Standard care
干预措施: Standard care (Behavioral)
Experimental Group
Standard care plus contingency management
干预措施: Standard care (Behavioral)
Experimental Group
Standard care plus contingency management
干预措施: Contingency management (Behavioral)
结局指标
主要结局
Alcohol abstinence
时间窗: 12 weeks
number of negative PEth samples
Group attendance
时间窗: 12 weeks
longest consecutive days attended groups
次要结局
未报告次要终点
研究者
Sheila Alessi
Associate Professor
UConn Health
