Intervention Comparative Effectiveness for Adult Cognitive Training
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 238
- 试验地点
- 2
- 主要终点
- Driving Simulator Average Lane Position Post Training
研究概览
简要总结
The study will compare the effect of broad and directed (narrow) technology-based training on basic perceptual and cognitive abilities in older adults and on the performance of simulated tasks of daily living including driving and fraud avoidance.
详细描述
Participants will be randomly assigned to four training conditions: broad training using either 1) Posit Science's web-based "BrainHQ" or 2) the video game Rise of Nations, or to directed training for 3) Instrumental Activities of Daily Living (IADL) training on both driving, American Association of Retired Persons (AARP)'s web-based older driver training program, and training for fraud avoidance, a web-based tutorial on finance and fraud, or 4) to an active control condition of puzzle solving. Training will take approximately 15-20 hr for each treatment condition. Before training begins, participants will take baseline ability tests of perception, attention, memory, and cognition, activities of daily living, as well as a driving simulator test for hazard perception, and a financial fraud recognition test. They will be tested again on these measures following training completion, and at a one-year follow-up from training completion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Outcomes Assessor)
盲法说明
Assessors will be blinded to study condition when administering the tests to participants
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 65 years and above
- •Plans to stay in the Tallahassee, Leon County area for the next year
- •Valid driver's license and drives at least once a month
- •Adequate cognitive ability assessed via telephone interview using the Wechsler Memory Scale III with story A score >6 or story B score >4.
排除标准
- •Terminal illness with life expectancy less than 12 months
- •Reports or exhibits a disabling visual condition assessed as the inability to read printed material
- •Reports or exhibits a disabling speech hearing and comprehension condition assessed by inability to hear and comprehend the screener's instructions
- •Reports or exhibits a disabling speech production condition assessed as the inability to respond with comprehensible English speech to the screener's queries
- •Reports or exhibits a disabling psychomotor condition assessed as the inability to use a keyboard and pointing device
- •Has completed the AARP driver training course
- •Has played the Rise of Nations video game
- •Has trained with Posit Science's "BrainHQ"
- •Has trained on the Mind Frontiers video game.
结局指标
主要结局
Driving Simulator Average Lane Position Post Training
时间窗: Baseline, Immediately after 4-week intervention training
Average lane position in a driving simulator measured at baseline and immediately after 4 weeks of training. Lane position measures the average deviation from the center of a lane while driving (values from -1 to 1), averaged across participants, where 0 represents perfect center, negative scores represent deviation to the left (from 0 to -1), and positive scores represent deviation to the right (from 0 to 1). Lane position indicates vehicle control and safety.
Driving Simulator Average Speed at One Year
时间窗: Baseline, One-year after 4-week intervention training
Average speed in a driving simulator measured at baseline and one year after 4 weeks of training. Speed is a continuous measure in miles per hour, with a minimum of 0 and no maximum. Speed may indicate risky driving behavior.
Driving Simulator Max Brake Compression at One Year
时间窗: Baseline, One-year after 4-week intervention training
Maximum brake compression in a driving simulator measured at baseline and one year after 4 weeks of training. Maximum brake compression measures the most that the brake pedal was compressed during driving, with a minimum of 0 and a maximum of 1. Maximum brake compression may indicate urgent stopping.
Driving Simulator Hazard Perception at One Year
时间窗: Baseline, One-year after 4-week intervention training
Driving simulator (scenarios including hazards) measures of speed, maximum brake compression, and lane position, at baseline and one year after 4 weeks of training. These measures provide an estimate of accuracy in driving scenarios that involve hazards in the DriveSafety simulator (using 3 parallel forms). All measures were transformed into Z scores and averaged in order to create a measure of overall driving performance, where higher scores represent more dangerous (worse) driving performance.
Speed of Processing at One Year
时间窗: Baseline, One-year after 4-week intervention training
Scores from Useful Field of View (UFOV) test and Digit Symbol Substitution Test, at baseline and one year after 4 weeks of training, which each provide a measure of speed of processing. Raw scores were transformed into z scores, UFOV reaction time scores were inverted, then UFOV and digit symbol scores were averaged in order to create an estimate of overall speed of processing, where higher scores represent better performance.
Knowledge About Driving at One Year
时间窗: One-year after 4-week intervention training
Test questions based on the American Association of Retired Persons driving course, measured one year after 4 weeks of training, with a minimum score of 0 and a maximum score of 3. Higher scores indicate more accurate knowledge of driving related information.
Driving Simulator Average Speed Post Training
时间窗: Baseline, Immediately after 4-week intervention training
Average speed in a driving simulator measured at baseline and immediately after 4 weeks of training. Speed is a continuous measure in miles per hour, with a minimum of 0 and no maximum. Speed may indicate risky driving behavior.
Driving Simulator Max Brake Compression Post Training
时间窗: Baseline, Immediately after 4-week intervention training
Maximum brake compression in a driving simulator measured at baseline and immediately after 4 weeks of training. Maximum brake compression measures the most that the brake pedal was compressed during driving, with a minimum of 0 and a maximum of 1. Maximum brake compression may indicate urgent stopping.
Driving Simulator Average Lane Position at One Year
时间窗: Baseline, One-year after 4-week intervention training
Average lane position in a driving simulator measured at baseline and one year after 4 weeks of training. Lane position measures the average deviation from the center of a lane while driving (values from -1 to 1), averaged across participants, where 0 represents perfect center, negative scores represent deviation to the left (from 0 to -1), and positive scores represent deviation to the right (from 0 to 1). Lane position indicates vehicle control and safety.
Useful Field of View Post Training
时间窗: Baseline, Immediately after 4-week intervention training
Useful field of view (UFOV) measured at baseline and immediately after 4 weeks of training. UFOV is measured as a response time in milliseconds, with lower times indicating quicker responses.
Digit Symbol Substitution Test Post Training
时间窗: Baseline, Immediately after 4-week intervention training
The Digit Symbol Substitution Test measured at baseline and immediately after 4 weeks of training. The Digit Symbol Substitution Test is measured through the number of items completed during a 90 second period, where higher scores indicate faster/better performance.
Useful Field of View at One Year
时间窗: Baseline, One-year after 4-week intervention training
Useful field of view (UFOV) measured at baseline and one year after 4 weeks of training. UFOV is measured as a response time in milliseconds, with lower times indicating quicker responses.
Knowledge About Finances and Fraud Post Training
时间窗: Immediately after 4-week intervention training
Test questions based on the Finance and Fraud training tutorial, measured immediately after 4 weeks of training, with a minimum score of 0 and a maximum score of 3. Higher scores indicate more accurate knowledge of finance and fraud related information.
Digit Symbol Substitution Test at One Year
时间窗: Baseline, One-year after 4-week intervention training
The Digit Symbol Substitution Test measured at baseline and one year after 4 weeks of training. The Digit Symbol Substitution Test is measured through the number of items completed during a 90 second period, where higher scores indicate faster/better performance.
Driving Simulator Hazard Perception Post Training
时间窗: Baseline, Immediately after 4-week intervention training
Driving simulator (scenarios including hazards) measures of speed, maximum brake compression, and lane position, at baseline and immediately after 4 weeks of training. These measures provide an estimate of accuracy in driving scenarios that involve hazards in the DriveSafety simulator (using 3 parallel forms). All measures were transformed into Z scores and averaged in order to create a measure of overall driving performance, where higher scores represent more dangerous (worse) driving performance.
Speed of Processing Post Training
时间窗: Baseline, Immediately after 4-week intervention training
Scores from Useful Field of View (UFOV) test and Digit Symbol Substitution Test, at baseline and immediately after 4 weeks of training, which each provide a measure of speed of processing. Raw scores were transformed into z scores, UFOV reaction time scores were inverted, then both UFOV and digit symbol scores were averaged in order to create an estimate of overall speed of processing, where higher scores represent better performance.
Knowledge About Driving Post Training
时间窗: Immediately after 4-week intervention training
Test questions based on the American Association of Retired Persons driving course, measured immediately after 4 weeks of training, with a minimum score of 0 and a maximum score of 3. Higher scores indicate more accurate knowledge of driving related information.
Fraud Detection Post Training
时间窗: Baseline, Immediately after 4-week intervention training
Percent confidence that a given vignette describing fraud is actually an example of fraud, measured at baseline and immediately after 4 weeks of training. Participants were given a vignette describing fraud (which was mixed in with vignettes not describing fraud) and were asked to give their percent confidence that this is actually an example of fraud. Higher confidence indicates higher accuracy when detecting fraud, with a minimum of 0 and a maximum of 100. Measures accuracy in discriminating fraud from non-fraud text-based scenarios (using 3 parallel forms).
Self-reported Difficulty With Instrumental Activities of Daily Living (IADLs) Post Training
时间窗: Baseline, Immediately after 4-week intervention training
Self-reported difficulties in completing instrumental activities of daily living, measured at baseline and immediately after 4 weeks of training, with a minimum score of 0 (indicating no difficulty) and a maximum of 3 (indicating severe difficulty). This is a modified short-form version of the Lawton IADL Items, used in the Multicenter AIDS Cohort Study (MACS).
Fraud Detection at One Year
时间窗: Baseline, One-year after 4-week intervention training
Percent confidence that a given vignette describing fraud is actually an example of fraud, measured at baseline and one year after 4 weeks of training. Participants were given a vignette describing fraud (which was mixed in with vignettes not describing fraud) and were asked to give their percent confidence that this is actually an example of fraud. Higher confidence indicates higher accuracy when detecting fraud, with a minimum of 0 and a maximum of 100. Measures accuracy in discriminating fraud from non-fraud text-based scenarios (using 3 parallel forms).
Self-reported Difficulty With Instrumental Activities of Daily Living (IADLs) at One Year
时间窗: Baseline, One-year after 4-week intervention training
Self-reported difficulties in completing instrumental activities of daily living, measured at baseline and one year after 4 weeks of training, with a minimum score of 0 (indicating no difficulty) and a maximum of 3 (indicating severe difficulty).This is a modified short-form version of the Lawton IADL Items, used in the Multicenter AIDS Cohort Study (MACS).
Knowledge About Finances and Fraud at One Year
时间窗: One-year after 4-week intervention training
Test questions based on the Finance and Fraud training tutorial, measured immediately after one year of training, with a minimum score of 0 and a maximum score of 3. Higher scores indicate more accurate knowledge of finance and fraud related information.
次要结局
- Numeracy at One Year(Baseline, One-year after 4-week intervention training)
- Technology Proficiency Post Training(Baseline, Immediately after 4-week intervention training)
- Numeracy Post Training(Baseline, Immediately after 4-week intervention training)
- Technology Proficiency at One Year(Baseline, One-year after 4-week intervention training)
- Reasoning Ability Post Training(Baseline, Immediately after 4-week intervention training)
- Miami Instrumental Activities of Daily Living Task Post Training(Baseline, Immediately after 4-week intervention training)
- Miami Instrumental Activities of Daily Living Task at One Year(Baseline, One-year after 4-week intervention training)
- Memory Ability at One Year(Baseline, One-year after 4-week intervention training)
- Reasoning Ability at One Year(Baseline, One-year after 4-week intervention training)
- Memory Ability Post Training(Baseline, Immediately after 4-week intervention training)
研究者
Neil Charness
Principal Investigator, Professor of Psychology
Florida State University