NCT00792779Unknown不适用
Protective Effect of Propofol Against Hemolysis in Patients Submitted to Gastroplasty
适应症
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Count erythrocytes
研究概览
简要总结
The purpose of this study is to determine if propofol could protect erythrocytes by directly scavenging free radicals from the blood current and increasing resistance of their cell membranes in patients submitted to gastroplasty.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients between BMI 40-50 kg/m2
排除标准
- •patients with BMI under 40 kg/m2 and over 50 kg/m2
- •alcohol users
- •illicit-drug users
- •patients in regular use of anti-depressants, proton bomb inhibitors or calcium canal blockers
- •patients transfused either recently, during the intra-operative period or within 10 hours post-operative
- •patients previously known to be hypersensitive to any drug that is used during the study
- •patients with any psychiatric disorder or dementia
结局指标
主要结局
Count erythrocytes
时间窗: After 10 hours post-surgery
次要结局
- Bilirubins(direct and indirect)(After 10 hours post-surgery)
研究者
研究点 (2)
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