JPRN-jRCTs031180209已完成2 期
Sequential therapy with vonoprazan, amoxicillin 7 days and vonoprazan, metronidazole, and sitafloxacin 7 days versus triple therapy with vonoprazan, amoxicillin, and metronidazole 7 days for early age Helicobacter pylori infection: a multicenter, open-label, randomized trial
Sue Soichiro0 个研究点目标入组 12 人开始时间: 2019年3月7日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 12
研究概览
简要总结
This study showed potential of 14-day sequential therapy containing vonoprazan and amoxicillin for 7 days followed by vonoprazan, metronidazole and sitafloxacin for 7 days and 7-day triple therapy with vonoprazan, amoxicillin and metronidazole. There was no problem in safety.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 <= 40age old（—）
- 性别
- All
入选标准
- •(1) A patient with Helicobacter pylori infection.
- •(2) A patient who can perform stool antigen test of Helicobacter pylori after 8 weeks from treatment completion.
- •(3)A patient who give a written informed consent.
排除标准
- •(1) A patient with history of Helicobacter pylori eradication.
- •(2) Pregnancy.
- •(3) Lactation.
- •(4) Patients allergic to penicillin.
- •(5) Past history of allergy for the drugs used in this study.
- •(6) A patient with brain and spinal cord disease.
- •(7) A patient with infectious mononucleosis.
- •(8) Severe liver dysfunction, serere renal dysfunction, severe heart dysfunction.
- •(9) Patient who is disualified for the study by physicians.
研究者
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