An Experimental Investigation Into the Impact of Socioeconomic Context on Biological Markers of Aging, Health and Mortality
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,350
- 试验地点
- 2
- 主要终点
- Mean Score on the Patient Health Questionnaire-9 (PHQ-9)
研究概览
简要总结
Paycheck Plus (PP) is a randomized controlled experiment (RCT) that explores the health and longevity effects associated with increasing the Earned Income Tax Credit (EITC). EITC is a national program that provides tax credits to low-income, disproportionately minority workers who file taxes. EITC is politically popular, having received bipartisan support. The EITC, along with state supplemental programs, have 7 million American families out of poverty. The investigators' preliminary data analyses show that the EITC has had large population health impacts, reversing declines in self rated health and survival among the poorest Americans.
详细描述
Poverty disproportionately impacts minority and rural populations and is very strongly correlated with poor health over the life cycle, and has been hypothesized to lead to a shorter, less healthy aging process. Poverty is associated with a greater burden of disease than smoking and obesity combined and accounts for the bulk of health disparities by race. It is widely believed that an antipoverty policy, such as Earned Income Tax Credit (EITC), could improve healthy aging among working-age low-income adults over the life cycle. It does so by increasing material hardship and psychological stress, two risk factors that are strongly correlated with biological markers of premature aging (e.g., shorter telomeres, higher cholesterol levels, and higher blood pressure).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •a US resident
- •Filed taxes
- •Earned <$30,000 in the previous year
- •Have a Social Security number
排除标准
- •Eligible for Supplemental Security Income or Social Security Disability Insurance
- •Have dependent children
结局指标
主要结局
Mean Score on the Patient Health Questionnaire-9 (PHQ-9)
时间窗: 4 Years
Depression will be measured using the subject's score on the PHQ-9.
EuroQol 5D5L
时间窗: 4 years
Health-related quality of life
次要结局
- Mean Body Mass Index (BMI)(2 Years)
- Telomere length(4 years)
- Mortality(4 years)