Health Effects of Coffee Consumption
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 118
- 试验地点
- 2
- 主要终点
- body weight
研究概览
简要总结
Epidemiological studies have indicated a positive health impact of coffee. Nevertheless, intervention studies testing the effect of daily coffee consumption over a longer period are lacking so far. Moreover, there is a lack of knowledge about the properties of different coffees and their influence on weight development. Therefore, we tested the effect of two coffees differing in their alkyl pyridine content over a period of 3 months on weight development.
详细描述
Participants were randomly associated to two groups, a test coffee group and a control coffee group. After coffee abstinence of 1 months, participants in both groups got a coffee machine and coffee pads for three months. Clinical data have been assessed before and after coffee abstinence and after 3 months of coffee consumption.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 69 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 18-69 years
- •BMI ≥27 kg/m2
- •coffee consumption of ≥3 cups per day
排除标准
- •new diagnosed type 2 diabetes during the last 6 months
- •severe diseases with hospital stay during the last 3 months
- •change of body weight of more than 2 kg per week during the last 4 weeks
- •smoking cessation during the last 3 months or planned during the study
- •acute infects
- •chronical diseases with except of type 2 diabetes mellitus
- •regular pharmacological therapy with except of oral antidiabetic medication or contraception
- •lack of contraception in women
- •breastfeeding
- •physical activity of more than 1 hour per day
结局指标
主要结局
body weight
时间窗: 4 months
body weight
次要结局
未报告次要终点
研究者
Stephan Martin
principal investigator
West German Center of Diabetes and Health