跳至主要内容
临床试验/NCT06862518
NCT06862518已完成不适用

Ultrasound Guided Serratus Anterior Plane Block Versus Thoracic Erector Spinae Plane Block for Post Operative Analgesia in Pediatrics Undergoing Thoracotomy: A Randomized Controlled Stud

Tanta University1 个研究点 分布在 1 个国家目标入组 105 人开始时间: 2023年7月1日最近更新:
干预措施
相关药物

试验速览

阶段
不适用
状态
已完成
入组人数
105
试验地点
1
主要终点
Total rescue analgesia consumption

研究概览

简要总结

This study is designed to compare the post operative analgesic effect of serratus anterior plane block versus thoracic erector spinae plane block in pediatrics undergoing thoracotomy

详细描述

The incidence of diseases that requires thoracotomy is low in the pediatric age group. Thoracotomy is a severe burden on children and is widely known to cause severe acute pain. This pain can be very distressing for both children and their parents. If not treated properly, it may acutely cause retention of secretion, atelectasis, ventilation-perfusion disorder and hypoxemia, together with a change in lung mechanics.

The serratus anterior plane block (SAPB) has also recently become more popular options for post-thoracotomy analgesia. SAPB involves local anesthetic injection in a plane superficial or deep to the serratus anterior muscle; in both these locations, it blocks the lateral cutaneous branches of intercostal nerves.

The erector spinae plane block (ESPB) is an ultrasound-guided deep plane interfascial block defined by Forero in 2016. It has been shown to provide thoracic and abdominal analgesia. When injected at the T5 transverse process level, the local anesthetic spreads anteriorly through the thoracolumbar fascia and reaches the ventral and dorsal rami of the spinal nerves and posteriorly to the gray and white rami communicantes of the sympathetic chain, providing a C7 to T8 sensitive block. Although it was first described as a chronic pain block, there are increasingly reports about its use in postoperative acute pain.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
2 Years 至 7 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Patient aged between 2 and 7 years.
  • Patient posted for the right or left thoracotomy under general anesthesia.

排除标准

  • Parents who refuse regional anesthesia.
  • Children who had any coagulation abnormality.
  • Deformity of the thoracolumbar spine.
  • Infection at the site of injection.
  • History of allergy to the local anesthetics.

研究组 & 干预措施

Control group

Active Comparator

Patients will receive general anesthesia alone

干预措施: Control group (Drug)

Serratus Anterior Plane Block (SAPB) group

Experimental

Patients will receive general anesthesia (GA) with ultrasound guided serratus anterior plane block 0.5 ml/kg 0.25% bupivacaine.

干预措施: Serratus Anterior Plane Block (SAPB) group (Drug)

Erector Spinae Plane Block (ESPB) group

Experimental

Patients will receive general anesthesia (GA) with ultrasound guided erector spinae plane block 0.5 ml/kg 0.25% bupivacaine.

干预措施: Erector Spinae Plane Block (ESPB) group (Drug)

结局指标

主要结局

Total rescue analgesia consumption

时间窗: 24 hours postoperatively

Rescue analgesia is planned based on the patients' face, leg, activity, cry, consolability score (FLACC) scores. Morphine 0.05 mg/kg IV was given as rescue analgesia in the case of FLACC scores above 3.The analgesic requirements in the first 24 h postoperatively were recorded.

次要结局

  • Time to 1st rescue analgesic requirement(24 hours postoperatively)
  • Degree of pain(24 hours postoperatively)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sarah Elsayed Mohamed Mohamed Hassan

Resident of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Tanta University

研究点 (1)

Loading locations...

相似试验