UVX as an Adjuvant in the Treatment of Fungal Keratitis
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 20
- 主要终点
- time of complete healing (days)
研究概览
简要总结
In this study, investigators want to find the effect of adjuvant collagen cross-linking in the treatment of fungal keratitis
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •fungal keratitis documented by culture or confocal scanning without any previous treatment
排除标准
- •Previous treatment
- •Thinning at presentation
- •Perforation
- •Associated with other microbial or viral keratitis
研究组 & 干预措施
conventional treatment
In this arm, patients with documented fungal keratitis undergo conventional medical treatment.
干预措施: topical voriconazole / levofloxacin systemic itraconazole (Drug)
conventional treatment +CXL
In this arm, patients with documented fungal keratitis undergo conventional medical treatment plus CXL, beginning on the first day
干预措施: topical voriconazole / levofloxacin systemic itraconazole (Drug)
conventional treatment +CXL
In this arm, patients with documented fungal keratitis undergo conventional medical treatment plus CXL, beginning on the first day
干预措施: CXL (Radiation)
结局指标
主要结局
time of complete healing (days)
时间窗: 180 days
time to scar formation (days)
次要结局
未报告次要终点
研究者
mohammad soleimani
assistant professor
Farabi Eye Hospital