Ultrasound-guided Rhomboid Intercostal Block Versus Retrolaminar Block for Postoperative Analgesia After Thoracoscopic Sympathectomy: A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Mean and Standard deviation of time to the first request of postoperative rescue analgesic (minutes) (mean±SD)
研究概览
简要总结
Background: Although thoracoscopic sympathectomy is made via small incisions, it is associated with severe postoperative pain. Both Rhomboid intercostal block (RIB) and Retrolaminar block (RLB) are recent techniques used for pain control after such procedures
Objectives: To compare the effectiveness of RIB and RLB in providing postoperative analgesia after thoracoscopic sympathectomy in adult patients and their impact on the patient's outcomes.
Patients and Methods: This prospective, randomized (1:1), double-blind clinical trial; will be carried out on 60 patients scheduled for elective thoracoscopic sympathectomy under general anesthesia at our hospital. Patients will be randomly allocated into two equal groups (30 patients each) and will receive: in group A; general anesthesia with intraoperative ipsilateral ultrasound-guided RIB, whereas in group B; general anesthesia with intraoperative ipsilateral ultrasound-guided RLB.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologists (ASA) physical status ≤ II
- •Age from 18 to 60 years
- •Body Mass Index (BMI) < 35 kg/m²
排除标准
- •American Society of Anesthesiologists (ASA) physical status > II
- •Age < 18 years or > 60 years
- •Body Mass Index (BMI) ≥ 35
- •Local infection at the puncture site
- •Altered mental status
- •Pregnant women
- •Allergy to study drugs
- •Chronic pain
- •Coagulation abnormalities or on anticoagulants
- •Severe hepatic or kidney disease
结局指标
主要结局
Mean and Standard deviation of time to the first request of postoperative rescue analgesic (minutes) (mean±SD)
时间窗: 24 hours after the end of surgery
The time interval between the block performance and the first request of postoperative analgesia
次要结局
- Mean and Standard deviation of Numeric Pain Rating Scale (NPRS) score (mean±SD)(24 hours after the end of surgery)
- Mean and Standard deviation of the total dose of the rescue analgesic consumed (milligrams) (mean±SD)(24 hours after the end of surgery)