Effect of ultrasound-guided superior laryngeal nerve block as an adjuvant to general anaesthesia on hemodynamic response to intubation in hypertensive patients: A randomized controlled trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To compare the change in mean blood pressure (MBP)/mean arterial pressure (MAP) from pre-intubation to 1 min post intubation in the two groups
研究概览
简要总结
The study is designed to investigate the effectiveness of ultrasound-guided superior laryngeal nerve block as an adjuvant to general anaesthesia on hemodynamic response to intubation in hypertensive patients. It was hypothesized that ultrasound-guided block of bilateral internal branch of superior laryngeal nerve would reduce hemodynamic response (measured using mean blood pressure) to intubation when compared to no block group when given as an adjuvant to general anaesthesia in hypertensive patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Controlled Hypertension/Hypertension with Diabetes/Hypertension with Coronary Artery Disease 2.Elective surgery requiring endotracheal intubation.
排除标准
- •Refusal to consent
- •ASA I/III/IV
- •Airway surgeries or surgeries requiring airway manipulation.
- •Any cardiomyopathy or ventricular dysfunction
- •Presence of any predictor of difficult intubation
- •Requirement of more than 2 attempts at endotracheal intubation
- •Contraindications to use of local anaesthetics or regional anaesthesia placement.
- •Preoperative hoarseness of voice or voice change.
- •Any group of patients where the quality of voice is essential, Eg. singers, teachers etc.
结局指标
主要结局
To compare the change in mean blood pressure (MBP)/mean arterial pressure (MAP) from pre-intubation to 1 min post intubation in the two groups
时间窗: preopeartive baseline value, pre intubation, 1 min after intubation
次要结局
- 1) ∆Systolic BP/Diastolic BP/Mean BP pre-intubation and at 3, 5 minutes post-intubation.(2) ∆Heart rate pre-intubation and at 1, 3, 5 minutes post-intubation.)
研究者
Krisnendu Sen
Post Graduate Institute of Medical Education and Research, Chandigarh.