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临床试验/NCT03381222
NCT03381222已完成不适用

Risk Factors of of Ascending Aortic Atheromatous Plaque in Thai Cardiac Surgical Patient

Mahidol University1 个研究点 分布在 1 个国家目标入组 239 人开始时间: 2018年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
239
试验地点
1
主要终点
Incidence of ascending aortic atheromatous plaque in Thai population

研究概览

简要总结

Background Incidence of perioperative stroke In cardiac surgery is 2.6-5.2%. Ascending aortic atheromatous plaque and stroke are strongly associated.

Propose of study To determine incidence of ascending aortic atheroma in Thai people To identify risk factors which associated with ascending aortic atheroma

Methodology After received standard general anesthesia and start sternotomy. Epiaortic scan will be performed by surgeon use L15-7i Phillips® ultrasound probe cover with sterile cover.

Five standard epiaortic views will be collected. Epiaortic clips will be review and determine about atheroma by two qualified echocardiographers. Atheroma more than third grade will defined to significant. Potential risk factors of atheroma will be gather from medical record

To assess the relationship between risk factors and atheroma a univariate analysis was performed using an unpaired t-test and a Chi-square test.

For higher accuracy regarding the impact of single risk factors, a multiple logistic regression analysis was also performed.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Age ≥ 18 years Schedule to cardiac surgery with sternotomy

排除标准

  • Abnormal ascending aortic anatomy such as: dissection, aneurysm

结局指标

主要结局

Incidence of ascending aortic atheromatous plaque in Thai population

时间窗: 1 year

incidence of ascending aortic atheromatous plaque

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Chaowanan Khamtuikrua

principal investigator

Mahidol University

研究点 (1)

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