HYPOTENSION PREDICTION INDEX FOR HEMODYNAMIC OPTIMIZATION IN MAJOR VASCULAR SURGERY
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- time weighted average of mean arterial presure under 65 mmHg
研究概览
简要总结
We will enroll patients scheduled for abdominal aortic aneurysm repair and divide in two groups; in the control group the hemodynamic optimization will be made based on standard cardiovascular parameters showed in the Hemosphere platform. In the interventional group the hemodynamic optimization will be made based on the hypotension prediction index.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •planned aortic surgery acceptance of written informed consent
排除标准
- •body mass index > 35 kg/m2
- •atrial fibrillation
- •urgent surgery
- •end-stage renal disease
- •pregnancy
- •refusal of the consent
研究组 & 干预措施
proactive group
in this group patients will be managed by a predictive hemodynamic algorithm
干预措施: proactive therapy (Other)
control group
drugs and fluids will be given based on mean arterial pressure and stroke volume variation respectively
结局指标
主要结局
time weighted average of mean arterial presure under 65 mmHg
时间窗: at the end of surgery
we will assess the magnitude of intraoperative arterial hypotension
次要结局
未报告次要终点
研究者
RUSSO ANDREA
MD
Fondazione Policlinico Universitario Agostino Gemelli IRCCS