Gender-specific Associations Between Quality of Life and Leukocyte Telomere Length: A Cross-sectional Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 164
- 主要终点
- leukocyte telomere length
研究概览
简要总结
Quality of life (QoL) is an important factor for successful aging. Telomere length is an indicator of cellular aging and cumulative biological stress and is thus related to health status and survival. However, the relationship between QoL and telomere length has not yet been examined. In this study we investigated the relationship between leukocyte telomere length (LTL) and QoL.
However, the relationship between overall QoL and LTL has not previously been investigated. Therefore, this study was conducted to examine the relationship between LTL and QoL. QoL was measured by the Korean version of the 36-item short-form health survey (SF-36), which is a multidimensional scale consisting of subjective evaluation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 55 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •married couple
- •apparently healthy subjects above 55 years
排除标准
- •Subjects who had experienced hormone therapy
- •Subjects who had been diagnosed with dementia, Parkinson's disease, stroke, ischemic heart disease, congestive heart failure, arrhythmia, depression, cancer, thyroid disorders, or chronic renal disease
结局指标
主要结局
leukocyte telomere length
时间窗: 8months
Leukocyte telomere length was measured as telomere repeat copy number relative to single gene copy number by quantitative real-time PCR
次要结局
未报告次要终点
研究者
Jung-Ha Kim
Professor
Chung-Ang University Hosptial, Chung-Ang University College of Medicine