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临床试验/NL-OMON41514
NL-OMON41514已完成不适用

Transcranial Magnetic Stimulation combined with electromyography and electroencephalography as a diagnostic and prognostic tool in Juvenile Myoclonus Epilepsy. - TMS-EMG/EEG as clinical tool in JME

Stichting Epilepsie Instellingen Nederland0 个研究点目标入组 122 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
122

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
12 至 99(—)

入选标准

  • In generally good health
  • Normal cognitive functioning
  • Speaking Dutch, English, French, German
  • 1st epileptic seizure OR >2 years seizure free
  • Diagnosis of JME confirmed
  • 12 years or older;for migraine:
  • 18 years or older
  • Migraine with aura (3/10 attacks) diagnosed according to ICHD-III criteria
  • One or more attacks per year
  • <8 attacks per month or <15 headache days per month (chronic migraine)
  • At least 1 attack in the year prior to the investigation.
  • The measurement will take place in the interictal phase, so a participant should not have had an attack 3 days prior or 3 days after the measurement.

排除标准

  • Use of medication with known effect on ion channel function (i.e. b-blocker)
  • Previous head/skull surgery (ferromagnetic material)
  • Diabetes mellitus (affects peripheral nervous system)
  • pregnancy (alters cortical excitability)
  • Neurological condition other than JME
  • Treated with anti-epileptic drugs before
  • Any neurological condition (including migraine)
  • Any psychiatric condition
  • 1st degree family members with epilepsy;for migraine:
  • Use of prophylactic medication up to 4 weeks prior to measurement
  • Use of attack medication less than 3 days prior to the measurement
  • Headache on the day of measurement

研究者

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