The Effect of Group Treatment for Depression: A Randomised Controlled Study of Metacognitive Therapy, Mindfulness and Support Groups
试验速览
- 阶段
- 不适用
- 入组人数
- 165
- 试验地点
- 1
- 主要终点
- Change from baseline on Hamilton depression scale
研究概览
简要总结
This study evaluates the effect of metacognitive group therapy on depression compared to mindfulness groups and supportive groups. The participants, all with a history of depression and with current symptoms of depression, will be randomized to one of the three group interventions.
详细描述
Metacognitive therapy (MCT) show promising results in alleviating depressive symptoms and reducing relapse of depression. However studies of MCT as a group intervention is limited and higher quality studies of the effectiveness of MCT is warranted. The present study aim to produce more conclusive evidence on the effect of MCT comparing MCT in groups with both and active control group and mindfulness based cognitive therapy (MBCT), which together with pharmacotherapy is currently one of the preferred treatment choices. Currently pharmacotherapy, cognitive therapy and MBCT seem to help 40-58% of the patients efficiently. The current studies of MCT indicate that this intervention may help a higher proportion of the patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Consent to participate
- •History of clinical depression
- •Current depressive symptoms
- •Verbal and cognitive abilities to complete the questionnaires during the study
- •Stable medication - if any medication is ordinated
- •Speaks fluently danish
排除标准
- •If criteria for psychosis, bipolar disorder or personality disorder is matched
- •known brain damage or mental retardation
- •substance abuse
- •women who are pregnant or breast feeding
研究组 & 干预措施
Metacognitive Therapy
干预措施: Metacognitive therapy (Behavioral)
Mindfulness based cognitive therapy
干预措施: Mindfulness based cognitive therapy, group (Behavioral)
Support groups
干预措施: Support groups (Behavioral)
结局指标
主要结局
Change from baseline on Hamilton depression scale
时间窗: 32 weeks
Change from baseline on Hamilton depression scale
时间窗: 8 weeks
次要结局
- Change from baseline on Ruminative Response Scale(32 weeks)
- Change from baseline on Becks depression inventory(32 weeks)
- Change from baseline on Becks Anxiety Inventory(32 weeks)
- Change from baseline on Metacognitive questionnaire(32 weeks)
- Change from baseline on Becks Anxiety Inventory(8 weeks)
- Change from baseline on Becks depression inventory(8 weeks)
- Change from baseline on Ruminative Response Scale(8 weeks)
- Change from baseline on Metacognitive questionnaire(8 weeks)
研究者
Tonny Elmose Andersen, phd.
Associate Professor
University of Southern Denmark