跳至主要内容
临床试验/NCT02259439
NCT02259439Unknown不适用

Assessment of Updated Evaluation Scores in Critically ILL COPD Patients Admitted to Assiut University Hospital

Nermeen Aly Mahmoud Abdel Aleem1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2012年9月最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
150
试验地点
1
主要终点
Calculate the mortality of exacerbated patients based on APACHE II and SOFA score, respiratory rate upon admittance, age, pO2/ FiO2 in the first few hours of admittance.

研究概览

简要总结

Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) represent a leading cause of morbidity and mortality.Patients admitted to hospital present higher mortality rates.The investigators lack the specific tools that allow us to easily classify and establish the individual prognosis for each patient during their hospitalization.

Rational of the study:to identify the predictive factors for hospital mortality in critically ill patients admitted to hospital due to an episode of COPD exacerbation.

详细描述

Material and Methods:

A) sociodemographic variables:

Age, sex, marital status, occupation, pack\year.

B) clinical variables:

1- Dyspnea measured by the Medical Research Council (MRC) scale and the COPD Assessment Test (CAT ) while stable, previous to admittance.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • We include for study all patients critically ill hospitalized for COPD exacerbation during the study period

排除标准

  • Patients who refuse to be admitted to hospital after having been properly informed, and their families as well, of the possible risks that they are assuming.
  • Specific diagnosis: pulmonary edema, rib fractures, aspiration, pleural effusion, etc. upon admission.
  • Other associated respiratory pathology that determines treatment: pulmonary fibrosis, kyphoscoliosis, neuromuscular pathology, upper airway obstruction, extensive tuberculosis sequelae.

结局指标

主要结局

Calculate the mortality of exacerbated patients based on APACHE II and SOFA score, respiratory rate upon admittance, age, pO2/ FiO2 in the first few hours of admittance.

时间窗: 24 hours

Calculate mortality caused by AECOPD depend upon APACHE II and SOFA score

次要结局

未报告次要终点

研究者

发起方
Nermeen Aly Mahmoud Abdel Aleem
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Nermeen Aly Mahmoud Abdel Aleem

chest department- faculity of medicine -Assiut university- Egypt

Assiut University

研究点 (1)

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