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临床试验/NCT00395837
NCT00395837已完成不适用

Efficacy of Lifestyle Changes in Modifying Practical Markers of Wellness and Aging

St. Anthony's Health Care1 个研究点 分布在 1 个国家目标入组 56 人开始时间: 2004年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
56
试验地点
1
主要终点
Cognitive performance (memory, psychomotor speed, reaction time, attention, cognitive flexibility)

研究概览

简要总结

To assess the impact of lifestylel changes upon measures of wellness and aging, in particular weight change, fitness measures, and cognitive performance. The hypothesis was that aerobic exercise would improve mental performance and measures of fitness.

详细描述

A 10-week, randomized control study conducted in a wellness center in St. Petersburg, Florida. Adults age 21-65, exercising less than 3 days/week. 56 subjects were randomized to a control or an intervention group. Subjects followed a diet with >30 grams of fiber and <16 grams of saturated fat daily, and were taught to reach 70-85% of their maximum heart rate 5-6 days/week, and to perform strength training 3 days/week, plus were asked to participate in 10-20 minutes of stress management activities daily. The study was designed to determine body composition, maximal aerobic capacity (VO2 max), total cholesterol/high-density lipoprotein (TC/HDL), and cognition.

Specific aspects ofcognitive performance were noted to increase with increasing levels of aerobic activity, but not with strength training, dietary fiber change, or stress managment.

Having established that the treatment group would exercise at different levels of intensity, additional subjects were recruited, and the cognitive performance of no exercise, moderate aerobic exercise, and frequent aerobic exercise could be compared with specific domains of cognitive performance: memory, psychomotor speed, reaction time, attention, and cognitive flexibility. The St Anthony's Institutional Review Board approved this research project.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •able to exercise 5-6 days per week

排除标准

  • •Free of major medical conditions, unable to exercise aerobically 5-6 days per week

结局指标

主要结局

Cognitive performance (memory, psychomotor speed, reaction time, attention, cognitive flexibility)

次要结局

  • Weight change
  • Body fat change
  • Changes in fitness (strength, flexibility, VO2max)
  • Cholesterol profile

研究者

发起方
St. Anthony's Health Care
申办方类型
Other

研究点 (1)

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