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临床试验/NCT04696601
NCT04696601撤回不适用

Rapid Screening for Olfactory Disorders in Covid-19 Infection

Centre Hospitalier Universitaire de Nice2 个研究点 分布在 1 个国家开始时间: 2021年1月8日最近更新:
适应症

试验速览

阶段
不适用
状态
撤回
试验地点
2
主要终点
Olfactory test

研究概览

简要总结

Loss of smell is very frequently found in Europe during Covid-19 attack. This symptom was not initially expected as part of the classic symptomatology. This loss of smell mainly concerns patients with few or no symptoms, without criteria of severity and usually treated on an outpatient basis. As a result, given the unexpected occurrence of this symptom (with less awareness in the general and medical population) and the potential risk of contamination of Covid+ and anosmic subjects (due to their less symptomatic form), it is interesting to be able to propose large-scale screening for loss of sense of smell in order to preferentially direct subjects diagnosed as anosmic towards RT-PCR-type screening. In the medium term, the loss of smell seems to persist after the infectious phase, with delayed or persistent recovery, which can lead to negative psychological repercussions.

The objective is to propose large-scale screening of the general population for loss of sense of smell during a pandemic period, in order to facilitate diagnostic orientation of the population. The diagnosis of loss of smell will be carried out using a simple olfactory test in the form of an olfactory stick to be smelled.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Screening
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Subject presenting himself at the covid-19 screening centre set up by the city of Nice

排除标准

  • Presence of a sensory deficit (auditory or visual) preventing the subject from answering the questions perfectly during the olfactory test.
  • Subject receiving cancer chemotherapy

结局指标

主要结局

Olfactory test

时间窗: Day 0

Sensitivity of the olfactory test (Olfascan) for measuring anosmia, compared to the reference diagnostic test (RT-PCR analysis).

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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