NCT00281710已完成4 期
Urinary Aquaporin 2 Excretion After Methylprednisolone in Fasting Healthy Humans
Regional Hospital Holstebro1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2005年10月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- u-AQP-2
研究概览
简要总结
We wanted to test the hypotheses that methylprednisolone up regulates u-AQP-2 in fasting healthy humans
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- Single
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •(1) Genders; both mal and female
- •(2) Age; 18- 65 years old
- •(3) BMI; below 30
- •(4) Females had to bee in oral contraceptive treatment
排除标准
- •(1) Clinical signs or history of disease in the heart, lungs, kidneys or endocrine organs
- •(2) Abnormal laboratory test (blood haemoglobin, white cell count, platelets, plasma sodium, plasma potassium, plasma creatinine, plasma albumin, plasma bilirubin, plasma alanine aminotransferase, plasma cholesterol and blood glucose)
- •(3) Albuminuria or glucosuria
- •(4) Cancer
- •(5) Arterial hypertension
- •(6) Alcohol abuse
- •(7) Use of tobacco
- •(8) Medical treatment, except oral contraceptives
- •(9) Pregnancy or breast feeding
- •(10) Medicine abuse
- •(11) Donation of blood less than 1 month before the study.
结局指标
主要结局
u-AQP-2
FeNa+
次要结局
未报告次要终点
研究者
研究点 (1)
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