NCT00241657已完成2 期
Immune Responses to BCG Vaccination in Malawi and the UK
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 试验地点
- 4
- 主要终点
- Delayed-type hypersensitivity
研究概览
简要总结
BCG vaccination has been found to provide greater protection against TB in the UK than in Malawi. This study compares immune responses in BCG-vaccinated and unvaccinated teenagers and young adults in Malawi and in the UK.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single
入排标准
- 年龄范围
- 12 Years 至 25 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BCG unvaccinated
- •HIV negative
- •Not pregnant
- •Informed Consent
排除标准
- •HIV positive
- •Seriously ill
结局指标
主要结局
Delayed-type hypersensitivity
cytokine responses (eg IFNg) to mycobacterial antigens
次要结局
- scar size
研究者
研究点 (4)
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