Differences in Sitting Versus Standing on Metabolic and Cardiovascular Measurements
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Carbon Dioxide Production
研究概览
简要总结
This investigations examined the effect that posture has on metabolic and cardiovascular measurements. Further, it will explore the potential for body weight status or physical activity to influence these relationships. All subjects will complete a seated condition and a standing condition in a counterbalanced manner.
详细描述
The purpose of the present study was to evaluate both metabolic and cardiovascular responses to acute bouts of computer work while sitting and standing. Cardiovascular measurements were made using continuous non-invasive blood pressure monitoring and metabolic measurements were made using indirect calorimetry. Subjects will be grouped and analyzed based upon the weight status of the subject. All subjects will complete a seated condition and a standing condition in a counterbalanced manner. Investigators hypothesize that metabolic and cardiovascular responses will be elevated in the standing condition compared to sitting.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •healthy adult
排除标准
- •Have a history of cancer, cardiac issues, hypertension, pulmonary disease, stroke, neurological or muscular dystrophy, uncontrolled diabetes, or any life threatening chronic conditions.
- •Are currently being treated for infectious mononucleosis, hepatitis, pneumonia, or other infectious diseases.
- •Are unable or unwilling to stand in one position continuously for 15-20 minutes at a time.
- •Use nicotine products, or non-contraceptive hormonal therapy (birth control is okay).
- •Are pregnant or trying to become pregnant.
- •Are not between 18 and 50 years of age.
结局指标
主要结局
Carbon Dioxide Production
时间窗: Approximately 15 minutes in each condition (sitting and standing)
Carbon Dioxide will be measured using indirect calorimetry.
Respiratory Exchange Ration (RER)
时间窗: Approximately 15 minutes in each condition (sitting and standing)
RER will be calculated using oxygen and carbon dioxide value measure from indirect calorimetry.
Systolic Blood Pressure (SBP)
时间窗: Approximately 15 minutes in each condition (sitting and standing)
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure SBP based upon beat-by-beat finger pressure.
Oxygen Consumption
时间窗: Approximately 15 minutes in each condition (sitting and standing)
Oxygen consumption will be measured using indirect calorimetry.
Diastolic Blood Pressure (DBP)
时间窗: Approximately 15 minutes in each condition (sitting and standing)
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure DBP based upon beat-by-beat finger pressure.
Ventilation
时间窗: Approximately 15 minutes in each condition (sitting and standing)
Ventilation will be measured using indirect calorimetry.
Heart Rate
时间窗: Approximately 15 minutes in each condition (sitting and standing)
Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure heart rate based upon beat-by-beat finger pressure.
次要结局
- Weight(1 minute)
- Body Composition(Approximately 15 minutes)
- Total Peripheral Resistance (TPR)(Approximately 15 minutes in each condition (sitting and standing))
- Body Mass Index (BMI)(1 minute)
- Height(1 minute)
- Stroke Volume(Approximately 15 minutes in each condition (sitting and standing))
- Cardiac Output (Q)(Approximately 15 minutes in each condition (sitting and standing))
- Muscle Oxygen Saturation(Approximately 15 minutes in each condition (sitting and standing))
研究者
Peter A. Hosick
Assistant Professor
Montclair State University