ENOUGH IBS: Evaluating Novel Uses of fibres on Gut Health in Irritable Bowel Syndrome

Monash University0 个研究点目标入组 26 人开始时间: 2019年5月8日最近更新: 2021年7月12日

适应症

试验速览

暂无简介。

•* IBS defined by ROME IV diganostic criteria.
•Potential participants not been formally diagnosed with IBS but presenting with the clinical features of the condition (i.e. recurrent abdominal pain and associated changes to bowel habit) will be referred to an appropriate medical doctor (either study gastroenterologist or their general practitioner) for formal diagnosis based on ROME IV criteria.
•* Currently symptomatic
•Eligible participants will then be invited to undertake screening to evaluate their IBS symptoms over five days. Symptoms will be assessed via a 100-mm VAS, where 0 mm indicates no symptoms and 100 mm represents the worst symptoms experienced. Participants whose scores are at least 30 mm for overall symptoms on the VAS will be included in the study.

•* Consumption of a special diet (i.e. low FODMAP, vegan diet).
•* Significant comorbidities (i.e. diabetes, chronic kidney disease).
•* Use of antibiotic therapies in the month preceding study commencement.
•* Consumption of prebiotics and probiotics in the month preceding study commencement.
•* Use of medication that potentially affects GI transit (i.e. hypomotility agents, laxatives).
•* Pregnancy or planning pregnancy.
•* Current smoker.
•* Unable to give written informed consent.

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