Effects of Combining Cognitive and Treadmill Training on Cognitive Function and Walking Performance-Exploration in Chronic Stroke Patient With Cognitive Impairment
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 2
- 主要终点
- Clock drawing test
研究概览
简要总结
Post-stroke cognitive impairment is common in stroke survivors. Cognitive function is related to walking ability. The dual task walking is required for daily activities, however, such ability is even more challenging than single walking for people with stroke. The purpose of present study is to investigate the effects of combining cognitive and treadmill training on cognitive function and dual task walking performance in chronic stroke patients with cognitive impairment.
详细描述
This is a single-blinded, randomized controlled trial with pre- and post-measurements. 24 subjects will be recruited, and randomly assigned to one of two groups: cognitive training during treadmill training group (experimental group) and treadmill training group (control group). The intervention for both group will be 30 minutes per session, 3 sessions per week for a total of 4 weeks. Statistical data analysis will use the SPSS 25.0. Baseline characteristics will be analyzed using independent t-test or Chi-square test. Repeated measures two-way analysis of variance (ANOVA) with Tukey's post-hoc analysis will be used to compare between time and groups. The significant level is set at 0.05.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age over 50 years old
- •chronic stroke (onset >6 months)
- •with mini-mental state examination (MMSE) score≧24
- •Montreal cognitive assessment (MoCA) score<26 (impaired cognition)
- •ability to walk independently for at least 10 meters without assistive devices or support
- •ability to read and write cognitive tests
排除标准
- •diagnosis of dementia
- •unstable physical condition
- •any neurological, psychiatric disorder, or diagnosed with learning disability which may affect participation in this study
- •visual or auditory disturbances
结局指标
主要结局
Clock drawing test
时间窗: 10 minutes
visuospatial function (score 1-10)
Trail-making test A&B
时间窗: 8 minutes
executive function (s)
Digit span test
时间窗: 8 minutes
memory (number)
Stroop test
时间窗: 10 minutes
attention (number)
次要结局
- Single walking performance- speed (cm/s)(3 minutes)
- Single walking performance-step time (s)(3 minutes)
- Cognitive dual task walking performance-cadence (steps/min)(3 minutes)
- Single walking performance-step length (cm)(3 minutes)
- Single walking performance-cadence (steps/min)(3 minutes)
- Cognitive dual task walking performance-speed (cm/s)(3 minutes)
- Cognitive dual task walking performance-step length (cm)(3 minutes)
- Cognitive dual task walking performance-dual task cost (%)(3 minutes)
- Cognitive dual task walking performance-step time (s)(3 minutes)