The Effect of tDCS Stimulation of Right Inferior Frontal Gyrus on Language Recovery in Speakers With Aphasia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 4
- 主要终点
- Picture naming task
研究概览
简要总结
There are two opposing hypotheses, namely the interference and laterality-shift hypotheses, regarding the role of the right hemisphere (RH) in language recovery following a left hemisphere damage. Transcranial direct current stimulation (tDCS) has received increasing attention as a potential complement to behavioural therapy.
This preliminary study aimed to examine the effect of excitatory (anodal) stimulation of right inferior frontal gyrus (IFG) on naming abilities of chronic people with aphasia (PWA) to examine the compensatory versus interference role of RH in language recovery, and to confirm the application of tDCS does not induce adverse effects on other cognitive and language functions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •People with chronic aphasia following the stroke
排除标准
- •history of seizure or epilepsy,
- •previous adverse reactions to TMS/tDCS,
- •having a pace-maker or a metal implanted in the brain
- •being pregnant
结局指标
主要结局
Picture naming task
时间窗: Immediately after the end of each treatment session and block
One hundred and sixty pictures of concrete nouns from the Snodgrass and Vanderwart (1980) picture set (colored version) were utilised to measure the percentage of object naming accuracy. In particular, these pictures were divided into Set A (training targets) and Set B (untrained generalization targets), with eighty stimuli in each set.
次要结局
- language task(Immediately after the end of each treatment block)
- Cognitive task(Immediately after the end of each treatment block)
研究者
Mehdi Bakhtiar
Assistant professor
The University of Hong Kong