Comparative evaluation of the efficacy of a commercially available collagen dressing (Collacote®) with autologous Platelet Rich Fibrin (PRF) membrane on the wound healing of palatal donor site of free gingival graft
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Immediate Bleeding
研究概览
简要总结
This study was conducted and compiled by Dr.Varsha Sharma, Dr.Ashish Kumar, Dr.Komal Puri, Dr.Mansi Bansal and Dr.Manish Khatri at Department Of Periodontology, Institute of Dental Studies and Technologies, Kadrabad, Modinagar, Uttar Pradesh, India
The study is a randomized control trial for comparison of the effect of commercially available collagen dressing (colla cote®) and autologous platelet rich fibrin on the wound healing of palatal donor site of free gingival graft. Assessment and comparison of various wound healing parameters, time required for complete epithelization of wound and considerable morbidity during the healing period was done.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 52.00 Year(s)（—）
- 性别
- All
入选标准
- •Systemically healthy patients aged 18 years or more, 2)Patient not under any medication for the past six months, 3)Patients requiring FGG either for reduced/ inadequate gingiva or gingival recession in the maxillary or mandibular anterior region, 4)Patients who have not undergone any palatal graft procedure in the past one year.
排除标准
- •Smokers, 2)Pregnant or lactating mothers, 3)Patients not maintaining oral hygiene.
结局指标
主要结局
Immediate Bleeding
时间窗: Immediate Bleeding:After suturing the donor area | Delayed Bleeding: Between 1st – 7th Post operative days | Pain Score, size, Toluidine blue test: 7th ,12th, 18th, 24th and 30th post-operative day. | Depth of wound: Before surgery, immediately post surgery, post application of dressing and on 12th, 24th and 30th post-operative days. | Hydrogen peroxide test for epithelialization: 7th & 8th, 12th &13th, 18th &19th, 24th &25th, 30th & 31st post-operative day.
Delayed Bleeding
时间窗: Immediate Bleeding:After suturing the donor area | Delayed Bleeding: Between 1st – 7th Post operative days | Pain Score, size, Toluidine blue test: 7th ,12th, 18th, 24th and 30th post-operative day. | Depth of wound: Before surgery, immediately post surgery, post application of dressing and on 12th, 24th and 30th post-operative days. | Hydrogen peroxide test for epithelialization: 7th & 8th, 12th &13th, 18th &19th, 24th &25th, 30th & 31st post-operative day.
Pain Score
时间窗: Immediate Bleeding:After suturing the donor area | Delayed Bleeding: Between 1st – 7th Post operative days | Pain Score, size, Toluidine blue test: 7th ,12th, 18th, 24th and 30th post-operative day. | Depth of wound: Before surgery, immediately post surgery, post application of dressing and on 12th, 24th and 30th post-operative days. | Hydrogen peroxide test for epithelialization: 7th & 8th, 12th &13th, 18th &19th, 24th &25th, 30th & 31st post-operative day.
Size of wound
时间窗: Immediate Bleeding:After suturing the donor area | Delayed Bleeding: Between 1st – 7th Post operative days | Pain Score, size, Toluidine blue test: 7th ,12th, 18th, 24th and 30th post-operative day. | Depth of wound: Before surgery, immediately post surgery, post application of dressing and on 12th, 24th and 30th post-operative days. | Hydrogen peroxide test for epithelialization: 7th & 8th, 12th &13th, 18th &19th, 24th &25th, 30th & 31st post-operative day.
Depth of wound
时间窗: Immediate Bleeding:After suturing the donor area | Delayed Bleeding: Between 1st – 7th Post operative days | Pain Score, size, Toluidine blue test: 7th ,12th, 18th, 24th and 30th post-operative day. | Depth of wound: Before surgery, immediately post surgery, post application of dressing and on 12th, 24th and 30th post-operative days. | Hydrogen peroxide test for epithelialization: 7th & 8th, 12th &13th, 18th &19th, 24th &25th, 30th & 31st post-operative day.
Toluidine blue test for epithelization
时间窗: Immediate Bleeding:After suturing the donor area | Delayed Bleeding: Between 1st – 7th Post operative days | Pain Score, size, Toluidine blue test: 7th ,12th, 18th, 24th and 30th post-operative day. | Depth of wound: Before surgery, immediately post surgery, post application of dressing and on 12th, 24th and 30th post-operative days. | Hydrogen peroxide test for epithelialization: 7th & 8th, 12th &13th, 18th &19th, 24th &25th, 30th & 31st post-operative day.
Hydrogen peroxide test for epithelization
时间窗: Immediate Bleeding:After suturing the donor area | Delayed Bleeding: Between 1st – 7th Post operative days | Pain Score, size, Toluidine blue test: 7th ,12th, 18th, 24th and 30th post-operative day. | Depth of wound: Before surgery, immediately post surgery, post application of dressing and on 12th, 24th and 30th post-operative days. | Hydrogen peroxide test for epithelialization: 7th & 8th, 12th &13th, 18th &19th, 24th &25th, 30th & 31st post-operative day.
次要结局
未报告次要终点