Thermal Images on Smartphones to Diagnose Bacterial Pneumonia in Children in Pakistan
试验速览
- 阶段
- 不适用
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- diagnosis of bacterial pneumonia
研究概览
简要总结
This is a prospective study of up to 250 participants, from birth to 18 months, who have already had a chest x-ray while a patient at the National Institute of Health (NICH) in Karachi, Pakistan. Participants will include both males and females as well as all races and ethnicities. Participants will have thermal pictures of their chest taken by trained study staff using a Smartphone and a FLIR ONE attachment. Thermal images will be read by trained radiologists to determine if bacterial pneumonia is present. Results of the thermal image will then be compared to the results of the chest x-ray. If additional images of the chest or other areas of suspected related infection are available, additional thermal images will be taken of the same location within 24 hours of the other image.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- — 至 18 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 months or younger;
- •patient at NICH Hospital in Karachi, Pakistan;
- •had chest x-ray within last 24 hours to determine diagnosis of bacterial pneumonia;
- •consent obtained from one parent
排除标准
- •thermal image cannot be done within 24 hours of chest x-ray
研究组 & 干预措施
Thermal Imaging
Imaging using a thermal camera
干预措施: FLIR ONE (Device)
结局指标
主要结局
diagnosis of bacterial pneumonia
时间窗: 24 hours
Pneumonia is defined as the presence of an airspace opacity, lobar consolidation, or interstitial opacities on a chest x-ray. This determination will be made by two independent radiologists blinded to each other's readings, clinical information and thermal images. If they agree that pneumonia is either present or absent, that will be the final diagnosis. If there is disagreement, a third independent, blinded radiologist will break the tie.
次要结局
- diagnosis of additional site of infection possibly related to bacterial pneumonia(up to a maximum of 28 days after original chest x-ray to diagnose pneumonia is taken)
研究者
Patricia L. Hibberd
Chief, Division of Global Health, Department of Pediatrics
Massachusetts General Hospital