NCT00458588已完成不适用
Adolescent Diet, Hormones and Breast Cancer Susceptibility
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 301
- 试验地点
- 10
- 主要终点
- Mean serum progesterone level in women not using hormonal contraceptives
研究概览
简要总结
RATIONALE: The amount and type of fat in the diet may affect hormone levels, bone mineral density, and breast density later in life. This may affect the risk of developing breast cancer. Learning about the long-term effects of diet on hormone levels, bone mineral density, and breast density may help the study of breast cancer in the future.
PURPOSE: This clinical trial is studying the long-term effect of adolescent diet on hormones and breast cancer risk in women previously enrolled in the Dietary Intervention Study in Children.
详细描述
OBJECTIVES:
Primary
- Determine the long-term effect of the Dietary Intervention Study in Children (DISC) to lower total fat and saturated fat intake during adolescence on serum progesterone levels in young women previously enrolled in the DISC study.
Secondary
- Determine the long-term effect of the DISC intervention on serum estradiol levels in these women.
- Determine the long-term effect of the DISC intervention on bone mineral density in these women.
- Determine the long-term effect of the DISC intervention on breast density in these women.
- Determine the long-term effect of the DISC intervention on the prevalence of metabolic syndrome in these women.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Mean serum progesterone level in women not using hormonal contraceptives
时间窗: Day 1 of treatment
次要结局
- Luteal phase serum estradiol level in women not using hormonal contraceptives(Day 1 of treatment)
- Bone mineral density of women who are not pregnant(Day 1 of treatment)
- Breast density of women who are not pregnant(Day 1 of treatment)
- Prevalence of metabolic syndrome(Day 1 of treatment)
研究者
研究点 (10)
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