NCT00627731已完成4 期
Phase 4, Randomized Study of Oral Glucocorticosteroid Administration in the Treatment of Acute Severe Asthma Exacerbation in Hospitalized Patients
Hamamatsu University1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2007年6月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Efficacy of oral prednisolone for the treatment of acute asthma
研究概览
简要总结
A comparison of oral prednisolone administration with intravenous methylprednisolone infusion in the treatment of acute asthma exacerbation in hospitalized patients. Oral glucocorticosteroids administration may be effective as intravenous high-dose methylprednisolone infusion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 16 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Asthma patients, who need hospitalized treatment, who do not respond with initial treatment including bronchodilator and IV methylprednisolone therapy
排除标准
- •Need for incubation
- •With severe complications
- •Received systemic glucocorticosteroid therapy in the previous 4 weeks
研究组 & 干预措施
1
Active Comparator
mPSL 240 mg per day for 5 days
干预措施: methylprednisolone sodium succinate (mPSL) (Drug)
2
Experimental
PSL 40mg per day for 10 days
干预措施: prednisolone (PSL) (Drug)
结局指标
主要结局
Efficacy of oral prednisolone for the treatment of acute asthma
时间窗: three-year
次要结局
- The safety of oral prednisolone for the treatment of acute asthma(three-year)
研究者
Naoki Inui
Department of Respiratory Medicine
Hamamatsu University
研究点 (1)
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