A comparative clinico-anatomical study to evaluate the efficacy of Marma Chikitsa and Anu Taila Pratimarsha Nasya in the management of Shushkakshipaka (Dry Eye Syndrome)
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Primary outcome will be Improvement in clinical symptoms like Feeling of Dryness,foreign body sensation,Blurring of vision, Hardness of eyelids,Difficulty in opening and closing of eye,Burning sensation and Intolerance to light.
研究概览
简要总结
In India, limited epidemiological data is available on dry eye syndrome. Recently a study from north India reported 32% prevalence of dry eye syndrome there. Out of them 81% were having severe dry eye syndrome based on symptoms. Another study from south India reported 1.46% Dry eye syndrome incidences.The authors predicted that within the end of next decade, large number of urban and rural populations would have dry eye syndrome.Dry eye syndrome is more common among women than men. Many factors such as poor nutrition, prolonged screen time etc. results in dry eye. Vitamin A deficiency in children due to diseases like measles, respiratory tract infection etc. also results in dry eye.Tear substitutes are the only affordable treatment modality with modern medical science. The duration of action of these tear substitutes is variable and are advised as per the need, only providing symptomatic relief. The preservatives present in these formulations are also a cause of dry eye, whereas those available without preservatives are not cost-effective. so there arises the need for the approach from Ayurveda to manage and prevent the disease Migraine. A study will be conducted to evaluate the efficacy of Anu Taila Pratimarsha Nasya and Marma Chikitsa in the management of Shushkakshipaka (Dry Eye Syndrome ). The study will involve 100 individuals randomly assigned to two groups: Each group will consist of 50 individuals.
Group A(Marma Chikitsa): - Marma Chikitsa will be administered to the individuals, targeting specific Marma points. Firstly Tila Taila will be applied and than 15-18 times pressure will be given to each Marma point once a day for duration of 2 month. .
Group B (Anu Taila Pratimarsha Nasya): - Individuals in this group will receive Pratimarsha Nasya of Anu Taila, which involves instilling 2-2 drops of Anu Tailainto each nostril once a day for duration of 2 months. Follow up will be taken after one month.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 16.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients having symptoms of Shushkakshipaka according to Ayurveda classics as well as modern science.
- •2.Patient willing to take Nasya or Marma Chikitsa.
- •3.Person who will ready to sign the consent form.
排除标准
- •1.Patients below the age of 16 years and above the age of 50 years.
- •2.Other type of Eye Disorders.
- •3.Patients with severe systemic disorders as uncontrolled Hypertension, Cardiac problem, Diabetes mellitus, Tuberculosis, Leprosy, Paralysis, malignant disease etc.
- •4.Pregnancy.
- •5.Use of other alternative medication during Ayurveda treatment.
结局指标
主要结局
Primary outcome will be Improvement in clinical symptoms like Feeling of Dryness,foreign body sensation,Blurring of vision, Hardness of eyelids,Difficulty in opening and closing of eye,Burning sensation and Intolerance to light.
时间窗: Baseline, after 2 months of intervention, follow up after every 15 days for 1 month.
Outcome will be accessed after 2 months of intervention, follow up after every 15 days for 1 month.
时间窗: Baseline, after 2 months of intervention, follow up after every 15 days for 1 month.
次要结局
未报告次要终点
研究者
Dr Sona Rani
Dr Sarvepalli Radhakrishnan Rajasthan Ayurved University, Jodhpur