ACTRN12624000595516已完成4 期
Evaluating and Comparing the Effects of Paracetamol and Ibuprofen on Wound Healing, MMP-9, and TGF-beta1 Levels in Patients Following Upper Third Molar Tooth Extraction.
Residency Training Program in Oral and Maxillofacial, Surgery, Faculty of Dentistry, Chiang Mai University0 个研究点目标入组 20 人开始时间: 2024年5月9日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 15 Years 至 30 Years（—）
- 性别
- All
入选标准
- •For the inclusion criteria, subjects were selected as patients who need to remove upper third molar tooth within an age range of 15-30 years, who were of healthy status (American Society of Anesthesiologists: ASA class I and II), and who reported a normal body mass index (BMI) within a range of 18.5-24.5 kg/m2. In addition, they were free from pathological conditions, denied having any history of chronic illnesses and drug allergies.
排除标准
- •The terms of exclusion were as follows: 1) Patients who were pregnant, heavy smokers, allergic to paracetamol, ibuprofen, or any anesthetic medications (e.g., mepivacaine and epinephrine-related drugs). 2) Patients who had undergone any pre-existing medical conditions such as hypertension, diabetes, liver disease, kidney disease, blood clotting disorders, and gastritis. 3) Patients who had wounds/injuries in various parts of their bodies prior to initiating the experimental study or those that had severe gingival inflammation (Gingival index > 2). 4). Patients who had taken medication or dietary supplements that could impact the wound healing process. 5) Patients who experienced psychological or communication disorders.
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