Evaluate the Relationship Between Computed Tomography Manifestation and Histopathological Classification of Thymic Epithelial Tumors
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 2
- 主要终点
- maximun diameter of the tumor
研究概览
简要总结
the World Health Organization (WHO) has proposed a classification of histopathological thymic tumor and it significance in prognosis. Chest computed tomography (CT) is the most common method to evaluate thymic epithelial tumors before operation. Therefore, the question is to predict the histopathological type of thymic epithelial tumors before surgery based on CT-scan images , to help determine treatment strategy and prognosis. In Vietnam, there are no published literature on this issue.
详细描述
- Introduction: the World Health Organization (WHO) has proposed a classification of histopathological thymic tumor and it significance in prognosis. Chest computed tomography (CT) is the most common method to evaluate thymic epithelial tumors before operation. Therefore, the question is to predict the histopathological type of thymic epithelial tumors before surgery based on CT-scan images , to help determine treatment strategy and prognosis. In Vietnam, there are no published literature on this issue.
- Materials and methods:
2.1. Cross-sectional descriptive study on 53 patients with diagnosed of thymoma by CT and had postoperative histopathology results as thymic epithelial tumors
2.2. Time and Place: in Departement of CTVS, Military Hospital 103, Vietnam from 10/2013 to 7/2017.
2.3. methods:
-
study in chest CT scan:
-
Measure the maximun diameter of the tumor
-
The contour: smooth contour or irregular contour
-
The shape: round, oval and plaque base on the ratio between long axis and short axis of the tumor
-
Some other characteristics: Degree of enhancement, Level of drug absorbed, Calcification, Invasion the local organs and Capsular destruction.
-
Histopathological study: based on the 2004 WHO classification:
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 71 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All of patient have a chest CT scan pre-operation and a result of thymic epithelial tumors postoperative histopathology
排除标准
- •Incomplete or loss the CT and postoperative histopathology
研究组 & 干预措施
CT and histopathological classification
With each histopathological type of thymic epithelial tumors, we measure the maximun diameter in chest CT scan. Comparison of some characteristics of the tumor on preoperative chest CT scans and histopathological type of thymic epithelial tumors .
干预措施: CT and histopathological classification (Other)
结局指标
主要结局
maximun diameter of the tumor
时间窗: 1 month
Measure the maximun diameter of the tumor in chest CT scan
次要结局
未报告次要终点
研究者
Le Viet Anh, MD
Principal Investigator
Military Hospital 103