CTRI/2008/091/000079招募中2 期
Role of a synbiotic/ probiotic (VSL#3) in the prevention of spontaneous bacterial peritonitis in cirrhotic Patients
Dept of Gastroenterology0 个研究点目标入组 250 人开始时间: 待定最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 250
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •All patients with liver cirrhosis with ascites having either history of prior SBP or ascitic fluid protein <1 gm/dl will be included in the study irrespective of etiology.
- •Cirrhosis will be diagnosed on the basis of clinical, radiological and/or histological ground Patients will be evaluated with complete medical history, clinical examination and baseline laboratory parameters: liver function test, renal function test, ascitic fluid analysis and disease specific further investigations as required. Cirrhosis will be classified according to Childâ??s-Pugh classification system.
排除标准
- •-Patients chronically treated with antibiotics (that disturb/alter normal gut flora) or lactulose during past 30 days.
- •-Patients having risk factor of small intestinal bacterial overgrowth other than cirrhosis - diabetes mellitus, history of abdominal surgery, immunomodulatory drugs, Alcoholic cirrhotics who continue to take alcohol.
- •-Patients with active or recent G.I. bleed (within prior 7 days).
- •-Patients with advanced HCC, renal failure and portal vein thrombosis
研究者
相似试验
招募中
早期 1 期
The effect of a synbiotic (probiotic and prebiotic) supplementation on patients with Non-Alcoholic Fatty Liver Disease (NAFLD): A proof of concept studyon-Alcoholic Fatty Liver DiseaseSLCTR/2018/042Durdans Hospital, 3, Alfred place, Colombo 3
进行中（未招募）
不适用
ASSESSMENT OF THE ROLE OF THE PROBIOTIC VSL3® IN THE TREATMENT OF POUCHITIS AFTER ILEAL POUCH-ANAL ANASTOMOSIS - VSL3This study aims to assess the bacterial flora in patients with healthy pouches and patients with have pouchitis. We aim to study the clinical and microbiological effectiveness of antibiotic and probiotic therapy in the modification of flora within these groups of patients.EUCTR2007-007977-21-GBeeds Teaching Hospitals Trust20
已完成
1 期
The Effect of Probiotic VSL#3 and Lifestyle Intervention in Obese Children with Non-Alcoholic Fatty Liver Disease (NAFLD)CTRI/2017/12/010997Babe Ke Ayurvedic Hospital VPO Daudhar106
已完成
不适用
The effect of synbiotic supplement on improvement of diabetics overweight status.Diabetes.Non-insulin-dependent diabetes mellitusIRCT2016062628386N2Vice chancellor for research, Alborz University of Medical Sciences100
已完成
Unknown
The effect of probiotics, paraprobiotics, and synbiotics on sleep metrics: systematic review and meta-analysissleepJPRN-UMIN000050539Tokyo Medical University Ibaraki Medical Center