JPRN-UMIN000005805已完成未知
Pilot study of intraarterial interferon/CDDP/5-fluorouracil combination chemotherapy for advanced hepatocellular carcinoma with translational research to predict efficacy - IFN/CDDP/5-FU for advanced HCC with translational research to predict efficacy
Faculty of Medical Sciences, University of Fukui0 个研究点目标入组 12 人开始时间: 2011年7月1日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 12
研究概览
简要总结
The response rate was significantly higher in patients treated with HAIC (37.5%) compared to that in patients treated with sorafenib (no response). The median overall survival (18.6 and 11.7 months) and progression-free survival (4.0 and 5.0 months) were similar between the sorafenib and HAIC groups, respectively. In the sorafenib group, 58.3% of the patients discontinued treatment compared to none in the HAIC group.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- ot applicable 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1) histrogically confirmed combined type hepatocellular carcinoma or sarcomatous change 2) previous therapy for hepatocellular carcinoma within 30 days 3) preceded chemotherapy (excluded transcatheter arterial embolization or adjuvant chemotherapy) 4) inadequate for administration of interferon, 5-FU or cisplatin 5) active double cancer 6) severe complication 7) refractory ascites or pleural effusion 8) inappropriate for entry onto this study in the judgment of the investigator
研究者
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