Ultra-Short Echo Time 1H MRI in Individuals With Thoracic Musculoskeletal Disorders
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Develop, optimize, and validate of 1H MRI sequences for assessment of lung structure and function
研究概览
简要总结
In this research study we want to learn about new ways to use MRI (Magnetic Resonance Imaging) to take clearer pictures of the lungs. We will be using types of MRI called UTE (Ultra Short Echo Time) and bSSFP (balanced Steady-State Free Precession) as well as traditional MRI. We also want to collect images and health information about lungs that are healthy or those in people with different kinds of lung, muscular, and bone diseases. This collection will help us in the future to better understand lung variations in health and disease.
研究设计
- 研究类型
- 观察性
- 观察模型
- 队列研究
- 时间视角
- 横断面
入排标准
- 年龄范围
- 5 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- Age ≥ 5 years
排除标准
- History of any comorbidity reviewed at the Screening phone call that, in the opinion of the investigator, might confound the results of the study or pose an additional risk to the subject.
- Standard MRI exclusion criteria as set forth by the CCHMC Radiology Department and IRC.
- Pregnancy
结局指标
主要结局
Develop, optimize, and validate of 1H MRI sequences for assessment of lung structure and function
时间窗: Through study completion, an average of 5 years
Structural 1H MRI parameters such as relative 1H signal intensity and radiologists interpretation will be compared to retrospective clinical images to determine viability of 1H MRI to assess lung disease.
Generate preliminary bSSFP UTE 1H MRI data in healthy individuals and individuals with thoracic musculoskeletal disorders.
时间窗: Through study completion, an average of 5 years
Free-breathing bSSFP UTE 1H MRI images will be compared to other conventional structural 1H MRI techniques and aspects like relative 1H signal between images will be compared.
次要结局
未报告次要终点
研究者
研究点 (1)
标识符
- NCT 编号
- NCT07845708
- 其他研究编号
- 2024-0256
日期
- 首次提交
- (8天前)
- 首次发布
- (昨天)
- 主要完成日期
- (3年后)
- 研究完成日期
- (3年后)
- 最近核实
- (29天前)
- 最近更新
- (昨天)
监管与共享
- FDA 监管药物
- 否
- FDA 监管器械
- 否
- 个体参与者数据共享计划
- 否
- 是否有结果
- 否