NCT04439084已完成不适用
COVID-19 in Patients With Chronic Liver Diseases
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,025
- 试验地点
- 23
- 主要终点
- Liver-related mortality
研究概览
简要总结
This study seeks to determine how COVID-19 affects the clinical outcome of patients with chronic liver disease, and whether the clinical course of COVID-19 is influenced by underlying chronic liver disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Confirmed diagnosis of COVID-19
- •Personal history of either
- •Chronic hepatitis C
- •Chronic hepatitis B
- •Alcoholic liver disease
- •Non alcoholic liver disease
- •Autoimmune hepatitis, Primary biliary cholangitis, Primary sclerosing cholangitis
- •Cryptogenic cirrhosis
- •Hepatocellular carcinoma
排除标准
- •Non-COVID-19 patient
结局指标
主要结局
Liver-related mortality
时间窗: 1 year
Death due to liver-related cause
All-cause mortality
时间窗: 1 year
Death due to any cause
Overall survival
时间窗: Up to 1 year
Patients will be assessed for this outcome for up to 1 year
Number of patients with hepatic decompensation
时间窗: Up to 1 year
Onset of hepatic decompensation due to COVID-19 disease; patients will be assessed for this outcome for up to 1 year
次要结局
- Number of participants requiring mechanical ventilation(Up to 1 year)
- Duration of hospitalization(Up to 1 year)
- Length of intensive care unit (ICU) stay(Up to 1 year)
- Number of patients requiring hospitalization(Up to 1 year)
研究者
研究点 (23)
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