EUCTR2010-019198-14-SE进行中（未招募）不适用
Icke-motoriska och hälsoekonomiska effekter av intermittent subkutan apomorfinbehandling vid Parkinsons sjukdom
Karolinska Universitetssjukhuset Huddinge0 个研究点目标入组 30 人开始时间: 2010年9月17日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •diagnosen Parkinsons sjukdom
- •kvarstående motoriska svängningar (wearing-off,”on-off”-perioder) trots individuellt utprovad behandling med L-dopa (med en perifer dekarboxylashämmare) med eller utan tilläggsbehandling (dopaminagonister, COMT alternativt MAO-B)
- •förekomst av fatigue, ångest och/eller depression enligt WOQ-19 (positivt svar på fråga 17 och/eller 18), NMSQuest (positivt svar på fråga 16 och/eller 17), FACIT-F (=34 poäng) och/eller HADS (>7 poäng)
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •pågående kliniskt signifikanta psykiatriska komplikationer
- •andningsdepression
- •psykotiska sjukdomar
- •leverinsufficiens
- •känd överkänslighet mot apomorfin eller någon annan ingående substans
- •svåra L-dopa inducerade dyskinesier
研究者
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