Investigating the effect of the Persian medicine product based on colchicum compared to placebo on pain and morning stiffness in patients with knee osteoarthritis: a triple-blind randomized clinical trial

Kerman University of Medical Sciences0 个研究点目标入组 70 人开始时间: 待定最近更新: 2023年8月21日

适应症

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•Age of 45-75 years old
•Diagnosis of knee osteoarthritis based on the criteria of the American College of Rheumatology, which is confirmed by a rheumatology specialist.
•The presence of moderate knee pain within 24 hours based on linear-visual pain scale (VAS) between 3.5 and 7.5 cm.
•Completing the inform consent form

•Pregnancy or breastfeeding
•Lack of physical and mental ability to answer questions
•Occurrence of debilitating disease during treatment
•History of allergy to herbal medicines
•use of alcohol or drug abuse
•History of systemic diseases such as heart failure, kidney failure and uncontrolled blood pressure
•Routine use of oral analgesic (except 500 mg oral acetaminophen daily)
•Consuming nutritional and medicinal supplements on a regular and daily basis
•Intra-articular injection of corticosteroid drugs during the last six months

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