NCT03616366Unknown不适用
The Mechanism and Prognosis of Pulmonary Circulation Dysfunction in Pulmonary Injury and Recovery
Chinese Academy of Medical Sciences, Fuwai Hospital1 个研究点 分布在 1 个国家目标入组 1,000 人开始时间: 2018年8月10日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- All cause death
研究概览
简要总结
Venous thromboembolism (VTE) is a condition which influenced by both environmental and genetic factors. This study is going to explore new significant Single nucleotide polymorphisms (SNPs) associated with VTE by Genome-Wide Association Studies (GWAS) and bioinformatics analysis. Transcriptomics and cytokine antibody array are also used to find new biomarkers of VTE's early diagnosis, severity and prognosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 14 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Chinese Han population older than 14 years old
- •Acute VTE patients diagnosed in 1 month
- •With informed consent
排除标准
- •Patients with psychosis
- •Patients with contraindications for computed tomographic pulmonary angiography (CTPA)
- •Chronic VTE
- •Recurrence of chronic VTE
结局指标
主要结局
All cause death
时间窗: 6 months
death
次要结局
- Venous thromboembolism (VTE) recurrence(6months)
- chronic thromboembolism pulmonary hypertension(CTEPH)(6 months)
研究者
Jianguo He
Chief of Pulmonary Vascular Disease Center
Chinese Academy of Medical Sciences, Fuwai Hospital
研究点 (1)
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