Risk of Malignancy in Endemic Long Standing Nodular Goitres: a Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- Rate of malignancy
研究概览
简要总结
To determine the incidence of thyroid cancer in patients with long standing goitres presenting for surgery.
详细描述
This is a prospective cohort study The objective is to determine the incidence of cancer in patients with long standing goitres( more than 10 years ) who present for surgery in Khartoum Teaching Hopspital - Sudan.
Introduction
goitre is endemic in Sudan with prevalence ranging between 5-42% in different regions of the country. Patients are referred for surgery only if they develop pressure symptoms.
The incidence of thyroid carcinoma is high in endemic goitrous areas. Determining the risk of cancer in patient with long standing goitres may help in early early referral and early surgical intervention.
Methods: This is prospective cohort study including 160 patients with long standing goitrers of 10 years or more who presented from March 2017 to September 2017 to Khartoum Teaching Hospital-Sudan
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients with long standing goitres of 10 years or more
排除标准
- 未提供
结局指标
主要结局
Rate of malignancy
时间窗: March 2017-September 2018
Rate of malignancy in resected goitre specimens
次要结局
未报告次要终点
研究者
Seifeldin Mahdi
Associate professor of surgery
University of Khartoum