A phase II, randomised feasibility basket trial of a personalised, multi-component, home-based exercise programme on disease-free survival among early-stage high-risk recurring cancers in Yorkshire

niversity of Hull0 个研究点目标入组 660 人开始时间: 2024年1月15日最近更新: 2024年7月22日

适应症

试验速览

暂无简介。

•1. Adults aged 18 or older
•2. Diagnosed with early-stage high-risk cancer, defined as:
•2.1. Non-small cell lung cancer: diagnosed with stages II or IIIA disease
•2.2. Breast: Triple-negative breast cancer: diagnosed with = stage II (defined as an Allred score < = 4 and her2 negative),
•2.3. Bowel: diagnosed with stage II, T4 disease only or any stage III disease
•3. Within 12 weeks of completing primary treatment (e.g., surgery +/- chemo and/or radiation therapy) with curative intent, or for those on adjuvant immunotherapy or tyrosine kinase inhibitors, as soon as they begin this phase of their adjuvant treatment,
•4. Willing and able to complete study measures and be randomised,
•5. Able to provide informed consent,
•6. Willing and able to engage remotely either by phone or video-based communications.

•1. Being treated for low-risk early-stage or incurable cancers,
•2. Having an irreversible unstable acute condition (e.g. acute infection, severe uncontrolled symptoms) or underlying chronic condition or disease (e.g. severe arthritis or dementia) that would impact study compliance.
•3. Mental capacity impaired to the extent that a course of systemic anti-cancer therapy is considered inappropriate by treating oncologist

发起方

niversity of Hull