TCTR20240416002已完成2 期
Intravenous Dexamethasone for Preventing Postoperative Nausea and/or Vomiting in Total Abdominal Hysterectomy: A randomized double-blinded, placebo-controlled trial
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 86
研究概览
简要总结
There was no significant difference in the incidence of PONV within 24 hours between the dexamethasone group and control group. The need for antiemetic drugs was not statistically different between groups, and without serious adverse events in both groups. The dexamethasone group experienced a lesser pain score than the control group at 24 hours after surgery. There was no difference in additional analgesic requirements.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 N/A (No limit)（—）
- 性别
- Female
入选标准
- •Participants were diagnosed with benign gynecologic conditions and scheduled for total abdominal hysterectomy with or without adnexal surgery.
排除标准
- •1.Had a known hypersensitivity to dexamethasone 2. Had conditions that might influence gastrointestinal motility (including previous bowel surgery, previous abdominal irradiation, chronic constipation, pancreatitis, peritonitis, hypothyroidism, and chronic use of drugs that impact intestinal peristalsis 3. Had underlying diabetes mellitus who got poor glycemic control 4. Were immunocompromised (tuberculosis, HIV Infection) 5. Experienced an intraoperative blood loss of more than 1,000 ml or blood loss that required blood transfusion.
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