Association of Admission Syndromic Diagnoses With ICU Mortality in a Mixed Adult Intensive Care Unit: Retrospective Cohort
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,248
- 试验地点
- 1
- 主要终点
- ICU mortality
研究概览
简要总结
This retrospective cohort study will evaluate whether syndromic clinical diagnoses present at ICU admission are associated with ICU mortality, independent of physiologic severity scores. Adult patients admitted to a tertiary mixed ICU during 2025 will be assessed.
详细描述
Data will be obtained retrospectively from the hospital information system and ICU clinical records. Variables will be recorded based on the first 24 hours after ICU admission. Demographics, admission characteristics, comorbidities, severity scores (APACHE II, SAPS, SOFA), and admission syndromic diagnoses (e.g., sepsis/septic shock, acute respiratory failure, ARDS, MODS) will be collected. The primary outcome is ICU mortality; secondary outcomes include ICU length of stay and ICU discharge disposition.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients (≥18 years) admitted to the ICU between January 1, 2025 and December 31,
- •If a patient has more than one ICU admission during the study period, only the first ICU admission will be included.
排除标准
- •ICU stay <24 hours.
- •Missing essential data preventing assessment of the primary outcome (ICU mortality) and/or calculation of severity scores (APACHE II, SAPS, SOFA).
研究组 & 干预措施
Adult ICU admissions (2025)
Adult patients (≥18 years) admitted to a tertiary mixed intensive care unit between January 1, 2025 and December 31, 2025. For patients with multiple ICU admissions, only the first ICU admission will be included. Data will be abstracted retrospectively from electronic medical records and ICU charts; variables will be recorded based on the first 24 hours after ICU admission.
结局指标
主要结局
ICU mortality
时间窗: From ICU admission until ICU discharge (end of index ICU stay), assessed up to 90 days
Death occurring during the index ICU stay (ICU mortality), abstracted from electronic medical records.
次要结局
- ICU discharge disposition(At ICU discharge (index ICU stay; assessed at the time of ICU discharge in the medical record, up to 90 days))
- ICU length of stay (LOS)(From ICU admission to ICU discharge (index ICU stay), assessed at ICU discharge (up to 90 days))
研究者
Mehmet Akif Yilmaz
Principal Investigator
Ataturk University