Effect of Pulpine and Combination of Pulpine With Polyamidoamine Dendrimer on Remineralization of Carious Affected Human Dentin
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- Remineralization & increase dentin density that is measured by using Vista Scan Radiography.
研究概览
简要总结
Remineralization of carious affected dentin
详细描述
Remineralization of Carious affected dentin by using Pulpine alone and combination of Pulpine with Polyamidoamine Dendrimer.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Presence of at least one class one carious posterior teeth in both left and right side.
- •Absence of spontaneous pain, Mobility and tenderness on percussion.
- •Radiographically, the preoperative inclusion criteria are, no internal or external resorption and no widening of the periodontal membrane space.
排除标准
- •Patients with poor oral Hygiene.
- •Evidence of Rampant Caries.
- •Teeth with periodontal involvement.
- •Poor general health condition.
研究组 & 干预措施
Combination of pulpine with Polyamidoamine Dendrimer
Removal of Caries infected dentin from the walls and floor of the cavity and then apply polyamidoamine Denrimer for 30 secs ,then washed out of the cavity followed by placement of Pulpine over affected Dentin.
干预措施: Pulpine with Polyamidoamine Dendrimer (Other)
Pulpine
Removal of Caries infected dentin from the walls and the floor of the cavity followed by application of Pulpine over affected Dentin.
干预措施: Pulpine with Polyamidoamine Dendrimer (Other)
结局指标
主要结局
Remineralization & increase dentin density that is measured by using Vista Scan Radiography.
时间窗: 6 months
Vista scan Radiography used to measure pixel grey value after 6 months.
次要结局
未报告次要终点
研究者
Mona Rizk Abo El Wafa Ahmed
Principal Investigator
Al-Azhar University