Traumatic Intracranial Hemorrhage in the Elderly: Prognostic Factors and Outcomes
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 主要终点
- Functional outcome assessed by the Glasgow Outcome Scale-Extended (GOSE)
研究概览
简要总结
This observational study aims to describe the clinical and radiological characteristics of older adults (aged 65 years and older) who experience traumatic bleeding in the brain, also known as traumatic intracranial hemorrhage. In older patients, even minor head injuries like a simple ground-level fall can lead to significant brain bleeding due to age-related changes, frailty, and the frequent use of blood-thinning medications.
The researchers will prospectively monitor geriatric patients admitted to the hospital with a traumatic brain bleed confirmed by a CT scan who are being treated conservatively (without surgery). During the hospital stay, the research team will collect data on the patients' pre-injury health status, current clinical condition, and specific findings on their brain scans.
The main goal of the study is to assess the patients' functional recovery and survival by the time they are discharged from the hospital. By observing these cases, the study seeks to identify which specific clinical signs and radiological factors help predict poor or favorable outcomes, ultimately aiming to improve the management and care of older adults with head trauma.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 65 years or older.
- •History of blunt or traumatic head injury.
- •CT-confirmed intracranial hemorrhage.
- •Conservatively managed patients.
- •Availability of clinical and radiological data.
- •Consecutive eligible patients during the defined study period.
排除标准
- •Non-traumatic intracranial hemorrhage.
- •Age less than 65 years.
- •Incomplete medical records.
- •Patients with major pre-existing intracranial pathology that prevents proper analysis.
- •Penetrating brain injury.
- •Surgically managed patients.
研究组 & 干预措施
Geriatric Patients with Traumatic Intracranial Hemorrhage
This cohort consists of conservatively managed patients aged 65 years or older with a history of blunt or traumatic head injury and CT-confirmed intracranial hemorrhage. Patients who are managed surgically or those with a penetrating brain injury are excluded from this cohort. Because this is an observational study, no experimental interventions are administered to the participants.
结局指标
主要结局
Functional outcome assessed by the Glasgow Outcome Scale-Extended (GOSE)
时间窗: Baseline
Functional outcome will be evaluated using the Glasgow Outcome Scale-Extended (GOSE). The GOSE scale ranges from 1 to 8, where higher scores indicate a better functional outcome. The results are subsequently categorized to define an unfavorable outcome as a GOSE score of 1-4, and a favorable outcome as a GOSE score of 5-8.
次要结局
未报告次要终点
研究者
Mostafa Mokhtar Mahmoud
Resident of Neurosurgery
Assiut University