The Effectiveness of Mesotherapy (Lidocaine and Proxicam) in the Treatment of Chronic Migraine
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 27
- 试验地点
- 1
- 主要终点
- Visual Analog Scale (VAS)
研究概览
简要总结
Mesotherapy is a type of injection frequently used in clinics. It is a treatment procedure that involves the injection of some drugs under the skin or into the skin. Mesotherapy is used in musculoskeletal system diseases, but it is reported that the effects of its use in migraine are uncertain.
详细描述
Migraine is one of the types of headaches. For the diagnosis of chronic migraine, the headache must last more than 15 days. Nerve blocks, oral medication and neuromodulation are recommended for migraine treatment.Mesotherapy is a type of injection frequently used in clinics. It is a treatment procedure that involves the injection of some drugs under the skin or into the skin. Mesotherapy is used in musculoskeletal system diseases, but it is reported that the effects of its use in migraine are uncertain. This study was planned to show the effectiveness of mesotherapy in patients with migraine.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
盲法说明
open label
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of chronic migraine disease
排除标准
- •Infection disease
- •Thyroid disease
- •Anemia disease
- •Systemic disease
研究组 & 干预措施
mesotherapy
All participants who received mesotherapy were monitored regularly for the following three months to assess their prognosis and ensure patient adherence to treatment.
干预措施: Lidocain (Drug)
结局指标
主要结局
Visual Analog Scale (VAS)
时间窗: 12 th week
VAS rates pain on a scale of zero to 10. It is explained to the participant that 10 points means unbearable pain, zero points means no pain, and the patient is asked to rate his pain between zero and ten. Higher scores indicate increased pain severity
The frequency of painful days per month
时间窗: 12th week
The participant is asked how many days she/he feels pain in a month.Higher numbers indicate increased frequency of painful days
次要结局
- Duration of attack per month(12th week)
- the number of analgesic per month(12th week)
研究者
Elif Ozyigit
Principal Investigator
Kanuni Sultan Suleyman Training and Research Hospital