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临床试验/NCT07761845
NCT07761845招募中不适用

Measurement of Red Cell Distribution Width/Albumin Ratio as a Predictive Tool for 30-day Mortality of Patients With Burn Injuries

Ain Shams University1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2026年8月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
30
试验地点
1
主要终点
mortality in burn patients

研究概览

简要总结

The aim of this study is to evaluate the prognostic utility of the red cell distribution width/albumin ratio (RAR), measured within 24 hours of hospital admission, in predicting 30-day mortality among patients with burn injuries.

详细描述

The aim of this study is to evaluate the prognostic utility of the red cell distribution width/albumin ratio (RAR), measured within 24 hours of hospital admission, in predicting 30-day mortality among patients with burn injuries.

Patients presenting with acute thermal injuries will be screened based on inclusion/exclusion criteria.

After consent, patients' characteristics (age, sex, weight), clinical parameters (total burn surface area, Abbreviated Burn Severity Index), and comorbidities will be recorded.

  1. Emergency Department (ED) management (Arrival and Initial Stabilization)

• Primary survey (ATLS principles): Immediate stabilization of Airway, Breathing, Circulation, Disability, Exposure (ABCDE).

  • Urinary catheter insertion to monitor urine output for proper resuscitation.
  • TBSA will be estimated using the Rule of Nines
  • All patients will be treated during the first 24 hours after burn injury guided by the Parkland Formula.
  1. In-Hospital Resuscitation (0-72 h)

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Age > 18 years.
  • •Both sexes.
  • •Patients with burn injuries (%TBSA >20%).
  • •Availability of complete laboratory data (RDW, albumin) on admission.
  • •Admission to ICU within 24 hours of burn injury.

排除标准

  • •Age <18 years.
  • •Patients with chronic hematologic disease.
  • •Pre-existing liver disease.
  • •Nephrotic syndrome.
  • •patients on chemotherapy.
  • •Patients with incomplete or missing lab records.
  • •Pregnant females.
  • •Patient or guardian refusal.

研究组 & 干预措施

• Patients with burn injuries (%TBSA >20%)

each patient will be followed for 30 days for mortality prediction

结局指标

主要结局

mortality in burn patients

时间窗: 30 days

To determine the correlation between Red Cell Distribution Width/Albumin on admission and 30 days hospital mortality in burn patients.

次要结局

  • ICU length of stay(30 days)
  • Requirements of inotropes or vasopressors(30 days)
  • Duration of mechanical ventilation(30 days)
  • To compare RDW/albumin ratio with Revised Baux score as a predictor of mortality in burn patient.(30 days)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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