NCT03196310终止不适用
Randomized Single Blinded First CMC Osteoarthritis Treatment: Therapy and Bracing Alone vs. Intra-Articular Corticosteroid Injection vs Intra-Articular Leukocyte Depleted Platelet Rich Plasma
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 74
- 试验地点
- 2
- 主要终点
- Disabilities arm shoulder and hand score
研究概览
简要总结
Single blinded PRP vs. Corticosteroid vs. Placebo (normal saline) intra-articular injection for basal joint arthritis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
Patients will be blinded to therapy they receive
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Stage 1-3 osteoarthritis of the basal joint
排除标准
- •Patients with Stage 4 1st carpometacarpal joint arthritis as described by Eaton
- •Patients who have received a corticosteroid injection in the last year to the 1st CMC joint on the proposed study side
- •Patients who have scaphotriquetral, radioscaphoid, or scaphotrapezial osteoarthritis
- •Patients who have concurrent DeQuervain's tenosynovitis or intersection syndrome or have been treated for either of these in the last 3 months
- •Patients undergoing evaluation of cervical radiculopathy
- •Patients with fibromyalgia or inflammatory rheumatic disease
- •Patients with Pressier disease, Kienbock's, or avascular necrosis of the scaphoid
- •Patients with any history of primary or secondary bone tumor
- •Patients that are pregnant or terminally ill
研究组 & 干预措施
PRP
Experimental
Intra-articular injection of platelet rich plasma.
干预措施: Platelet Concentrate (Drug)
Normal Saline
Placebo Comparator
Intra-articular injection of normal saline
干预措施: Normal Saline (Other)
Corticosteroid
Active Comparator
Intra-articular injection of kenalog.
干预措施: Corticosteroid injection (Drug)
结局指标
主要结局
Disabilities arm shoulder and hand score
时间窗: 1 year
functional score
次要结局
- Pinch Strength(1 year)
研究者
研究点 (2)
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