DRKS00023623已完成不适用
Posttraumatc headache - pain related evoked potentials and conditioned pain modulation as possible biomarkers for the identification of risk patients - PTH-PREP
eurologische KlinikBG Universitätsklinikum Bergmannsheil gGmbH0 个研究点目标入组 46 人开始时间: 2020年11月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 46
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •Inclusion criteria for patients:
- •- Acute or persistent headache resulting from a traumatic head injury
- •- The headache developed within 7 days of any of the following: the head injury, regaining consciousness after the head injury, discontinuation of medication that interferes with the ability to feel or report a headache after the head injury
- •- The headache is not better explained by another ICHD-3 diagnosis
- •Inclusion criteria for healthy control subjects:
- •- none of the exclusion criteria is met
- •- Present declaration of consent
- •- No abnormal result in the questionnaire or physical examination
- •- no use of drugs with peripheral or central nervous effects /side effect
- •- no neurological or psychiatric illness
排除标准
- •Exclusion criteria for patients:
- •- Age <18 years
- •- no declaration of consent
- •- Average pain intensity in the last 4 weeks <2 (NRS 0-10)
- •- Current pain intensity <2 (NRS 0-10)
- •- Insufficient knowledge of German or other communication problems
- •- Neuropathic pain syndromes
- •- Headache illness known before the accident
- •- Treatment with topical local anesthetics for <7 days in the last 6 weeks or for >7 days in the last 4 months
- •- Treatment with topical capsaicin in the past 6 months
- •- Epilepsy treated with anticonvulsants
- •- Psychiatric illness treated with anticonvulsants or antidepressants with a proven effect on neuropathic pain
- •- Other pain localization with a pain intensity =6 (NRS 0-10) on =15 days / month
- •- Other severe systemic or focal CNS affection
- •- Other central or peripheral neurological disorders
- •- peripheral arterial occlusive disease (except for stage Fontaine I)
- •- Serious cognitive or psychiatric impairment
- •Exclusion criteria for healthy control subjects:
- •- Age <18 years
- •- no declaration of consent
- •- Average pain intensity in the last 4 weeks> 2 (NRS 0-10)
- •- Current pain intensity >0 (NRS 0-10)
- •- Insufficient knowledge of German or other communication problems
- •- Neuropathies, radiculopathies, or nerve lesions
- •- Chronic pain syndromes
- •- Treatment with topical local anesthetics for the past 6 weeks
- •- Treatment with topical capsaicin in the past 6 months
- •- Epilepsy treated with anticonvulsants
- •- Psychiatric illness treated with anticonvulsants or antidepressants with a proven effect on neuropathic pain
- •- Other severe systemic or focal CNS affection
- •- Other central or peripheral neurological disorders
- •- peripheral arterial occlusive disease (except for stage Fontaine I)
- •- Serious cognitive or psychiatric impairment
研究者
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